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Evaluation of the evidence on acetaminophen use and neurodevelopmental disorders using the Navigation Guide methodology (Prada, et al, 2025) ehjournal.biomedcentral.com/ar Today in not #ketamine and not #psychedelics news, the world's most overused medicine, #acetaminophen (aka #paracetamol #tylenol ) linked to #add #adhd #autism -- this in addition to risk-taking behaviors pmc.ncbi.nlm.nih.gov/articles/

BioMed CentralEvaluation of the evidence on acetaminophen use and neurodevelopmental disorders using the Navigation Guide methodology - Environmental HealthBackground Acetaminophen is the most commonly used over-the-counter pain and fever medication taken during pregnancy, with > 50% of pregnant women using acetaminophen worldwide. Numerous well-designed studies have indicated that pregnant mothers exposed to acetaminophen have children diagnosed with neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD), at higher rates than children of pregnant mothers who were not exposed to acetaminophen. Methods We applied the Navigation Guide methodology to the scientific literature to comprehensively and objectively examine the association between prenatal acetaminophen exposure and NDDs and related symptomology in offspring. We conducted a systematic PubMed search through February 25, 2025, using predefined inclusion criteria and rated studies based on risk of bias and strength of evidence. Due to substantial heterogeneity, we opted for a qualitative synthesis, consistent with the Navigation Guide’s focus on environmental health evidence. Results We identified 46 studies for inclusion in our analysis. Of these, 27 studies reported positive associations (significant links to NDDs), 9 showed null associations (no significant link), and 4 indicated negative associations (protective effects). Higher-quality studies were more likely to show positive associations. Overall, the majority of the studies reported positive associations of prenatal acetaminophen use with ADHD, ASD, or NDDs in offspring, with risk-of-bias and strength-of-evidence ratings informing the overall synthesis. Conclusions Our analyses using the Navigation Guide thus support evidence consistent with an association between acetaminophen exposure during pregnancy and increased incidence of NDDs. Appropriate and immediate steps should be taken to advise pregnant women to limit acetaminophen consumption to protect their offspring’s neurodevelopment.

Building rituals as a writer

I am an easily distracted squirrel. I am also a storyteller. If I want my stories to go out into the world, I need a way to focus my squirrel nature on my writing.

For this, I think I need to establish some rituals for dreaming and writing. I’ve no idea how or what will work. No ideas at all.

Please offer your ideas – all ideas are good at this stage.

If you think it will help, a boost or reblog would be lovely.

#ADD#ADHD#rituals

NFL free agency: Browns add OT Kilian Zierer to roster, release WR and RB

Despite the team being off from training camp practice on Sunday, the beat goes on for the ever-changing…
#NFL #HoustonTexans #Houston #Texans #add #agency #and #browns #by #cleveland-browns-free-agency #cleveland-browns-news #cleveland-browns-roster-players #dawgs #Football #free #front-page #kilian #nature #ot #rb #release #roster #To #wr #zierer
rawchili.com/nfl/260212/

Me this morning: For the first time in ages I did everything I had to do this week, so I can feel relaxed this weekend. That's great, I think I'll spontaneously clean my apartment a bit.

My demand avoidance when I realize I actually *have* to clean my apartment this weekend: REEEEEEEEEEEEEE
#ADD #ADHD

Tuota noin. Meikä sai näin 39-vuotiaana ADD-diagnoosin. (Harmillisesti se ei vaihtunut yleisen ahdistuneisuushäiriön tilalle, vaan tuli sen rinnalle, ainakin näin toistaiseksi) Ei kai tässä, lääkityksiä alan kokeilemaan. Pelottaa kyllä vähän. Olen kuitenkin tähän saakka ns. suoriutunut elämässä. Toki tavoite on muutakin kuin vain suoriutua, eli siksi kai tähänkin prosessiin lähdin. #ADD #ADHD

Replied in thread

@estruppi Complêtement pour : j'ai ajouté un add-e ( add-e.at/ ) sur mon vélo VTC, plusieurs avantages : a) je garde mon super vélo des années 2000 b), j'ajoute que 0,7kg de moteur et 1,6kg de batterie, donc 2.3kg au total au poids de mon vélo : la reste léger, même si la batterie tombe en panne; c) maintenant, pour aller le matin au boulot, je gagne 25% de temps et je ne transpire plus, donc pas de douche, donc je gagne encore du temps; d) si je veux faire du musculaire, de toute façon >25km/h le moteur s'arrête. et e) si je veux, le système s'enlève totalement en moins de 5min.
#velotaf #adde #add-e

add-e - der E-Bike Nachrüstsatz für dein FahrradStartseite - add-e - der E-Bike Nachrüstsatz für dein Fahrradadd-e NEXT verwandelt Dein Fahrrad in ein superleichtes E-Bike! add-e NEXT Komponenten im Detail Antriebseinheit ZUM SHOP Das Herzstück des Systems ist …

Pouring old mineral oil in a bottle -> realizing I'd better label that bottle -> getting tape and a pen... pen doesn't work -> look if the pen uses a refill cartridge -> falling into pen rabbit hole on the internet looking for pens, refills, ways to upgrade this pen, new pens, pen reviews... -> 1+ hr later -> looking at installing CPU fans -> going into the kitchen for some snacks and seeing the bottle: OH RIGHT that's what I was doing. Now what about that pen...

Raiders mailbag: Will Raiders add a safety or cornerback ahead of training camp?

The 2025 season will be here before you know it. The Las Vegas Raiders’ rookies report to training…
#NFL #LasVegasRaiders #LasVegas #Raiders #a #add #ahead #and #black #camp #category-community-comments #Cornerback #Football #front-page #las-vegas-raiders-news #las-vegas-raiders-training-camp #Mailbag #NFLTrainingCamp #of #or #pride #safety #silver #Training #will
rawchili.com/nfl/202504/

"Sorry, we don't serve dogs coffee." The waiter was sympathetic, "Even to neoboxers."
Tau whined.
"Bebe knows Tau has an important mission to rescue orphans and he was up all night with that pretty Miss Epsilon discussing his etchings."
Ears back with a lolling tongue, Tau tried not to chuckle.
The waiter blushed, confusing Bebe. She looked at Tau, "Did Bebe say something wrong? Does Tau have anything to #add?"
Tau barked.
"One fishberry smoothie to keep Tau's secret. Comin' right up!"
#wss366

Replied in thread

#TimeTravelingGhost Part 19: Episode 2: 1937: The Hindenburg Part D

#Wss633 & #TimeTravelAuthors 7/11 Romance/love triangle?

“The Hindenburg,” I repeated. “And that’s not your sister, but you?”

I took a sip of my Champagne cocktail while I put my thoughts in order. I savored the taste to settle my mind. The drink was simple but elegant, not quite up to the ones at the Folies Bergère. There, they rimmed the glass with vibrantly colored sugar crystals and poured with flair. This had been served politely, without fanfare. That kind of flourish would have clashed with the quiet elegance of the Hindenburg. It was a fine drink, fitting for the airship.

Emily stared at me. “You drank that?”

“Yes, try yours. It is quite good.”

“No, you’re a ghost and you drank that!”

I hadn’t thought about it, but I couldn’t remember any stories about ghosts drinking. Didn’t Buddhists even make a big deal out of how some ghosts drank and ate but could never feel nourished? That must relate to why I stayed inebriated for so short a time. The first part, not the bit about the hungry ghosts. I found the light fizz and warmth of the drink very satisfying.

I shrugged in reply. “So it seems.”

“And your clothes, they aren’t very appropriate.”

True, they were 21st-century casual: jeans and a short brown sweater dress. They must have passed as a costume at the Folies Bergère. I imagined myself in a dress matching Emily’s and wah lah I was in period attire. I #add(ed) a black pearl necklace for flair.

“Don’t do that!” Emily hissed. “You’re putting on a spectacle.”

“My bad.” She was right, of course. Doing things like that where I could be seen wasn’t clever. “This ghost thing is all new to me.”

“I’m new to ghosting and even I know that was stupid,” she added.

I’d wished for a travel companion, and I guessed Emily Pang was it. Not that she was romance material. Heavens, no. I like other women that way, but sharp-tongued women never appealed to me. Besides, she wasn’t even my type. I would just help her and then ask her if she wanted to do some traveling. That’s all.