J Nat Prod. 2022 Jan 28;85(1):176-184. doi: 10.1021/acs.jnatprod.1c00946. Epub 2022 Jan 10.

+++ #Cannabinoids +++

Block Cellular Entry of SARS-CoV-2 and the Emerging Variants

Richard B van Breemen 1, Ruth N Muchiri 1, Timothy A Bates 2, Jules B Weinstein 2, Hans C Leier 2, Scotland Farley 2, Fikadu G Tafesse 2
Affiliations Expand
PMID: 35007072 PMCID: PMC8768006 DOI: 10.1021/acs.jnatprod.1c00946

#Corona #Cannabis #Cannabinoide #Endocannabinoidsystem des Menschen [#ECS] #WEEDMoB #Streeck

https://www.europesays.com/uk/117764/ Body’s Own Cannabinoids May Help Control Trauma-Linked Fear #2AG #anxiety #BrainResearch #cannabinoids #endocannabinoids #fear #Health #MentalHealth #neurobiology #Neuroscience #NorthwesternUniversity #Psychology #PTSD #trauma #UK #UnitedKingdom

A farewell to Pepe Mujica, who recently passed away and really led by example ( ESPAÑOL MÁS ABAJO)

ENG: "He established an agenda of rights that marked his administration by fire; he promoted the 8-hour working day for rural workers when he was Minister of Livestock, and during his term of office, the day of the rural worker was declared, which is celebrated every 30 April; The law on the voluntary interruption of pregnancy (with the main rationale of accompanying women in their decision and not as a mere act of ending a life); the regulation of marijuana consumption, which put Uruguay in the international spotlight as a testing ground for the legalisation of all drugs in order to put an end to a war that only leaves deaths along the way."

ESP: "Consagró una agenda de derechos que marcaron a fuego su gestión; promovió las 8 horas para el trabajador rural siendo ministro de Ganadería, y durante su mandato se declaró el día del peón rural que se celebra cada 30 de abril; el matrimonio igualitario, la ley de interrupción voluntaria del embarazo (con la fundamentación principal de acompañar a las mujeres en la decisión y no como un mero acto de poner fin a una vida); la regulación del consumo de marihuana, con la que puso al Uruguay en la mira internacional como un campo de prueba hacia la legalización de todas las drogas para poner fin a una guerra que solo deja muertos por el camino."

https://otromundoinfo.wordpress.com/2025/05/14/naides-es-mas-que-naides/

#pepemujica #pepe_mujica
#cannabis #cannabismedicinal #cannabislegalisierung #legaliza
#legalization #cannabinoide #thc #cbd #cbn #thca #maconha #marijuana #marihuana #PatientCare #Cannabinoids #Endocannabinoide #EfectoSéquito #entourageeffect

ENG: "Over 70% Of Studies Back Medical Cannabis In Cancer Treatment, Meta-Analysis Finds." They searched 10.000 published papers. Keep that in mind, next time you read the old " more reasearch is needed".

Will gladly share a proven protocol in comments if requested. Nothing for sale. Strictly educational purposes to correct such rampant intentional misinformation.

https://www.forbes.com/sites/dariosabaghi/2025/04/21/over-70-of-studies-back-medical-cannabis-in-cancer-treatment-meta-analysis-finds/

ESP: "Meta análisis de 10.000 estudios científicos publicados reveló una tendencia significativa ( 71.4%) que apoya el potencial terapéutico del cannabis, en particular para el manejo de los síntomas relacionados con el cáncer y efectos anticancerígenos directos."

Con gusto aclaro dudas sobre cómo usarlo para este fin. Solo pregunten en comentarios. No se vende nada, el fin es educativo para contrarrestar tanta desinformación intencional.

Enlace autotraducido:
https://www-forbes-com.translate.goog/sites/dariosabaghi/2025/04/21/over-70-of-studies-back-medical-cannabis-in-cancer-treatment-meta-analysis-finds/?_x_tr_sl=auto&_x_tr_tl=es&_x_tr_hl=es-419&_x_tr_pto=wapp&_x_tr_hist=true

#cancer #Cannabinoids #medicine
#marijuana #cannabismedicinal
#medicalcannabis #healing #cbda #chemotherapy #cbd #quimioterapia
#thc #thca #regenerativemedicine
#herbalist #healthare #healthscience
#medical #marijuananews #cbn #homeostasis #chemo #pharmagreed
#endocannabinoidsystem #weed
#endocannabinoide #marihuana
#pharma #pharmaceuticals #healthcare #HealthCrisis #health

Edited for hashtags

https://youtube.com/shorts/mi7cS5z2cJY?feature=shared

ENG: Observational study on medical #cannabis use for 300 people over 50 proves medical #weed effectiveness. Patients favor high CBD low THC oral dosing ( balanced 1:1), to reduce arthritic/chronic pain and help sleep without having to chain smoke/vape. If CBD dominantes there is almost no psychotropic effect.

ESP: Ciencia moderna confirma que #marijuana medicinal alivia dolor crónico, artrítis y sueño. Estudio con 300 personas de más de 50 años revela que pacientes prefieren gotas o comestibles altos en CBD y bajos en THC. Extracto 1:1 de flor resulta aún más efectivo y evita tener que fumar/vapear para sostener efectos analgésicos/ansiolíticos. De dominar el CBD el efecto psicotropico es nulo o mínimo.

#memercredi #viernesdememes #humour #funny #humor #salud #regenerativemedicine #humornegro
#HumourNoir #science #health
#chronicillness #ChronicPainMemes
#chronicpain #thc #cbd #cbn #thca
#sleep #arthritis #cannabinoids
#cannabismedicinal #cannabismedical

ALT-TXT: Monochrome photo of old indigenous woman holding a huge joint between her swollen fingers. Text: SIGNS OF AGING: Swollen Joints

Für #Anwälte und #Anwältinnen und #Klagende: Wirklich evidente Informationen kann man da bekommen. Das sind die absoluten Spitzenleute, was die Forschung zu #Cannabinoiden anbelangt.

https://cannabis-med.org/de [deutsch]

https://cannabis-med.org/ [english]

The aim of the International Alliance for #Cannabinoid Medicines (#IACM) is to advance knowledge on #cannabis, #cannabinoids, the #endocannabinoidsystem and related topics, especially their therapeutic potential. #Merz #Söder #CarmenWegge #ACM

Für Anwälte und Anwältinnen und Klagende: Wirklich evidente Informationen kann man da bekommen. Das sind die absoluten Spitzenleute, was die Forschung zu #Cannabinoiden anbelangt.

https://cannabis-med.org/de [deutsch]

https://cannabis-med.org/ [english]

The aim of the International Alliance for #Cannabinoid Medicines (#IACM) is to advance knowledge on #cannabis, #cannabinoids, the #endocannabinoidsystem and related topics, especially their therapeutic potential.

@researchbuzz

Nuevo estudio de YALE afirma que los cannabinoides, CBD, CBG y CBN podría dar alivio del dolor seguro, eficaz, sin efecto psicotrópico ni la fuerte dependencia de los opioides.

https://news.yale.edu/2025/01/21/cannabinoids-offer-new-hope-safe-and-effective-pain-relief

"A new scientific review on #cannabis and cancer concludes that a variety of cannabinoids—including #delta-9 #THC, #CBD and #cannabigerol (#CBG)—”show promising potential as anticancer agents through various mechanisms,” for example by limiting the growth and spread of tumors."

“#Cannabinoids exhibit significant anticancer activities such as apoptosis induction, autophagy stimulation, cell cycle arrest, anti-proliferation, anti-angiogenesis, and metastasis inhibition.”

https://www.marijuanamoment.net/marijuana-components-show-promising-potential-as-anticancer-agents-study-finds-though-mechanisms-of-action-are-still-a-mystery/?

Nasal sprays might help protect the upper respiratory tract, but what about the lungs? What if we had something we could vaporize and fill the lungs with that might raise the minimum infectious dose of SARSCoV2 by inhibiting cell entry?

Something that isn't psychoactive -- like CBD -- and could be used by everyone? What if regulated, plentiful, and inexpensive CBD extract could be found at every pharmacy?

"Retrospective clinical studies support antiviral activities of CBD, Δ9-THC, and cannabinoid mixtures as do some prospective clinical trials, but appropriately designed clinical trials of safety and efficacy of antiviral cannabinoids are urgently needed."

https://portlandpress.com/clinsci/article/137/8/633/232928/Antiviral-activities-of-hemp-cannabinoids

#Cannabinoids as novel #AntiInflammatory drugs

by Prakash Nagarkatti, et al.
October, 2009

Abstract:

"Cannabinoids are a group of compounds that mediate their effects through cannabinoid receptors. The discovery of Δ9-tetrahydrocannabinol (#THC) as the major psychoactive principle in marijuana, as well as the identification of #cannabinoid receptors and their endogenous ligands, has led to a significant growth in research aimed at understanding the physiological functions of cannabinoids. Cannabinoid receptors include CB1, which is predominantly expressed in the brain, and CB2, which is primarily found on the cells of the immune system. The fact that both CB1 and CB2 receptors have been found on #immune cells suggests that cannabinoids play an important role in the regulation of the immune system. Recent studies demonstrated that administration of THC into mice triggered marked apoptosis in T cells and dendritic cells, resulting in immunosuppression. In addition, several studies showed that cannabinoids downregulate #cytokine and chemokine production and, in some models, upregulate T-regulatory cells (Tregs) as a mechanism to suppress #inflammatory responses. The #endocannabinoid system is also involved in #immunoregulation. For example, administration of endocannabinoids or use of inhibitors of enzymes that break down the endocannabinoids, led to immunosuppression and recovery from immune-mediated injury to organs such as the liver. Manipulation of endocannabinoids and/or use of exogenous cannabinoids in vivo can constitute a potent treatment modality against inflammatory disorders. This review will focus on the potential use of cannabinoids as a new class of anti-inflammatory agents against a number of inflammatory and autoimmune diseases that are primarily triggered by activated T cells or other cellular immune components."

Executive summary

- Cannabinoids, the active components of #CannabisSativa, and endogenous cannabinoids mediate their effects through activation of specific cannabinoid receptors known as cannabinoid receptor 1 and 2 (CB1 and CB2).

- The cannabinoid system has been shown both in vivo and in vitro to be involved in regulating the immune system through its immunomodulatory properties.

- Cannabinoids suppress inflammatory response and subsequently attenuate disease symptoms. This property of cannabinoids is mediated through multiple pathways such as induction of apoptosis in activated immune cells, suppression of cytokines and chemokines at inflammatory sites and upregulation of FoxP3+ regulatory T cells.

- Cannabinoids have been tested in several experimental models of autoimmune disorders such as #MultipleSclerosis, #RheumatoidArthritis, #colitis and #hepatitis and have been shown to protect the host from the pathogenesis through induction of multiple anti-inflammatory pathways.

- Cannabinoids may also be beneficial in certain types of #cancers that are triggered by #ChronicInflammation In such instances, cannabinoids can either directly inhibit tumor growth or suppress inflammation and tumor angiogenesis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/

https://cannabis-med.org/en/bulletin

#Science/Human: #Cannabis may be effective in the treatment of major depressive disorder

https://cannabis-med.org/bulletin/iacm-bulletin-of-14-january-2024

Science/Human: Cannabis can improve symptoms in refractory cancer-related pain

https://cannabis-med.org/bulletin/iacm-bulletin-of-17-december-2023

IACM: 13th #IACM Conference on #Cannabinoids in #Medicine in 2024 to be held online

https://cannabis-med.org/bulletin/iacm-bulletin-of-3-december-2023

#FridaysForFuture #RestoreNature #letztegeneration #GemeinsamGegenRechts #WirSindMehr #fff #Greta
#klima #WHES24 #ard #zdf #Papst #Vatikan #fff

https://www.forbes.com/sites/ajherrington/2024/01/11/study-shows-cannabis-has-the-potential-to-prevent-and-treat-covid-19/?sh=48c621fa2574

@dalhousie_university researchers:“Cannabinoids have the potential to be used as a preventive approach to limiting the susceptibility and severity of #COVID19 infections by preventing viral entry, mitigating oxidative stress, and alleviating the associated #cytokinestorm.”

study also found they could be used to treat patients with #LongCovid…“Post- #SarsCoV2 infection, #cannabinoids have shown promise in treating symptoms associated with post-acute long COVID-19…"