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#cannabinoid

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Anna Kalinovsky<p>Our new research on cannabinoid signaling in cerebellar development and function is published in eNeuro.<br><a href="https://mastodon.social/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoid</span></a> <a href="https://mastodon.social/tags/cerebellum" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cerebellum</span></a> <a href="https://mastodon.social/tags/Purkinje" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Purkinje</span></a> <a href="https://mastodon.social/tags/DevelopmentalNeuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevelopmentalNeuroscience</span></a> <a href="https://mastodon.social/tags/endocannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endocannabinoid</span></a> <a href="https://mastodon.social/tags/indianauniversity" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>indianauniversity</span></a> <a href="https://mastodon.social/tags/synapses" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>synapses</span></a> <a href="https://mastodon.social/tags/braindevelopment" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>braindevelopment</span></a></p><p><a href="https://www.eneuro.org/content/12/7/ENEURO.0400-24.2025" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">eneuro.org/content/12/7/ENEURO</span><span class="invisible">.0400-24.2025</span></a></p>
JADe (he, him)<p>ENG: Today, first saturday of May, hundreds of thousands will march not just for a plant, but for personal freedom, civil rights, a culture of peace and the right to care for people in their family/community without Big Pharma's synthetic poison. Check a science-based better <a href="https://mastodon.cr/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabis</span></a> ointment recipe: </p><p><a href="https://jorge--alban--dobles-blogspot-com.translate.goog/?m=1&amp;_x_tr_sl=es&amp;_x_tr_tl=en&amp;_x_tr_hl=es-419&amp;_x_tr_pto=wapp" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jorge--alban--dobles-blogspot-</span><span class="invisible">com.translate.goog/?m=1&amp;_x_tr_sl=es&amp;_x_tr_tl=en&amp;_x_tr_hl=es-419&amp;_x_tr_pto=wapp</span></a></p><p>ESP: Hoy, primer sábado de mayo, cientos de miles marcharán no solo por una planta, sino en defensa de libertad personal, los derechos civiles, una cultura de paz y la posibilidad de mejorar la salud de su familia/comunidad sin los venenos sintéticos de las grandes farmacéuticas. Una mejor receta de ungüento de <a href="https://mastodon.cr/tags/marihuana" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>marihuana</span></a> , respaldada por la ciencia, en:</p><p><a href="https://jorge-alban-dobles.blogspot.com/?m=1" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jorge-alban-dobles.blogspot.co</span><span class="invisible">m/?m=1</span></a></p><p><a href="https://mastodon.cr/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoid</span></a> <a href="https://mastodon.cr/tags/thc" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>thc</span></a> <a href="https://mastodon.cr/tags/cbd" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbd</span></a> <a href="https://mastodon.cr/tags/cbn" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbn</span></a> <a href="https://mastodon.cr/tags/regenerativemedicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>regenerativemedicine</span></a> <a href="https://mastodon.cr/tags/maconha" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>maconha</span></a> <a href="https://mastodon.cr/tags/mota" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>mota</span></a> <a href="https://mastodon.cr/tags/medicinal" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medicinal</span></a> <a href="https://mastodon.cr/tags/civilrights" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>civilrights</span></a> <a href="https://mastodon.cr/tags/freedom" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>freedom</span></a> <a href="https://mastodon.cr/tags/peace" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>peace</span></a> <a href="https://mastodon.cr/tags/weed" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>weed</span></a> <a href="https://mastodon.cr/tags/thca" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>thca</span></a> <a href="https://mastodon.cr/tags/marchamundialmari" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>marchamundialmari</span></a> <a href="https://mastodon.cr/tags/mmj" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>mmj</span></a> <br><a href="https://mastodon.cr/tags/marijuana" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>marijuana</span></a> <a href="https://mastodon.cr/tags/cannabismedicinal" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabismedicinal</span></a><br><a href="https://mastodon.cr/tags/medicalcannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medicalcannabis</span></a> <a href="https://mastodon.cr/tags/healing" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>healing</span></a> <a href="https://mastodon.cr/tags/cbda" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbda</span></a><br><a href="https://mastodon.cr/tags/herbalist" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>herbalist</span></a> <a href="https://mastodon.cr/tags/healthare" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>healthare</span></a> <a href="https://mastodon.cr/tags/healthscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>healthscience</span></a><br><a href="https://mastodon.cr/tags/medical" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medical</span></a> <a href="https://mastodon.cr/tags/marijuananews" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>marijuananews</span></a> <a href="https://mastodon.cr/tags/marijuana" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>marijuana</span></a> <a href="https://mastodon.cr/tags/homeostasis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>homeostasis</span></a> <a href="https://mastodon.cr/tags/chemo" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>chemo</span></a> <a href="https://mastodon.cr/tags/pharmagreed" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pharmagreed</span></a> <br><a href="https://mastodon.cr/tags/endocannabinoidsystem" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endocannabinoidsystem</span></a><br><a href="https://mastodon.cr/tags/endocannabinoide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endocannabinoide</span></a> <a href="https://mastodon.cr/tags/corporategreed" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>corporategreed</span></a> <br><a href="https://mastodon.cr/tags/pharma" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pharma</span></a> <a href="https://mastodon.cr/tags/pharmaceuticals" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pharmaceuticals</span></a> <a href="https://mastodon.cr/tags/healthcare" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>healthcare</span></a> <a href="https://mastodon.cr/tags/HealthCrisis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>HealthCrisis</span></a> <a href="https://mastodon.cr/tags/health" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>health</span></a><br><a href="https://mastodon.cr/tags/solarpunk" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>solarpunk</span></a> <a href="https://mastodon.cr/tags/solarpunksunday" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>solarpunksunday</span></a> <br><a href="https://mastodon.cr/tags/cannabisculture" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabisculture</span></a> <a href="https://mastodon.cr/tags/cannabislegalisierung" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabislegalisierung</span></a></p>
EURACTIV Health<p>Denmark and Sweden see rise in semisynthetic <a href="https://eupolicy.social/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoid</span></a> poisonings <a href="https://www.euractiv.com/section/health-consumers/news/denmark-and-sweden-see-rise-in-semisynthetic-cannabinoid-poisonings/?utm_source=dlvr.it&amp;utm_medium=mastodon" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">euractiv.com/section/health-co</span><span class="invisible">nsumers/news/denmark-and-sweden-see-rise-in-semisynthetic-cannabinoid-poisonings/?utm_source=dlvr.it&amp;utm_medium=mastodon</span></a></p>
Euractiv<p>Denmark and Sweden see rise in semisynthetic <a href="https://masto.ai/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoid</span></a> poisonings: <a href="https://masto.ai/tags/Cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoid</span></a>-induced poisonings are leading to more hospital admissions as drug traffickers target puff bars, <a href="https://masto.ai/tags/gummies" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>gummies</span></a>, and <a href="https://masto.ai/tags/ecigarettes" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ecigarettes</span></a>. <a href="https://www.euractiv.com/section/health-consumers/news/denmark-and-sweden-see-rise-in-semisynthetic-cannabinoid-poisonings/?utm_source=mastodon&amp;utm_medium=dlvr.it" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">euractiv.com/section/health-co</span><span class="invisible">nsumers/news/denmark-and-sweden-see-rise-in-semisynthetic-cannabinoid-poisonings/?utm_source=mastodon&amp;utm_medium=dlvr.it</span></a></p>
Karl Theodor<p>Für <a href="https://mastodon.social/tags/Anw%C3%A4lte" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Anwälte</span></a> und <a href="https://mastodon.social/tags/Anw%C3%A4ltinnen" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Anwältinnen</span></a> und <a href="https://mastodon.social/tags/Klagende" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Klagende</span></a>: Wirklich evidente Informationen kann man da bekommen. Das sind die absoluten Spitzenleute, was die Forschung zu <a href="https://mastodon.social/tags/Cannabinoiden" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoiden</span></a> anbelangt.</p><p><a href="https://cannabis-med.org/de" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">cannabis-med.org/de</span><span class="invisible"></span></a> [deutsch]</p><p><a href="https://cannabis-med.org/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">cannabis-med.org/</span><span class="invisible"></span></a> [english]</p><p>The aim of the International Alliance for <a href="https://mastodon.social/tags/Cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoid</span></a> Medicines (<a href="https://mastodon.social/tags/IACM" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>IACM</span></a>) is to advance knowledge on <a href="https://mastodon.social/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabis</span></a>, <a href="https://mastodon.social/tags/cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoids</span></a>, the <a href="https://mastodon.social/tags/endocannabinoidsystem" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endocannabinoidsystem</span></a> and related topics, especially their therapeutic potential. <a href="https://mastodon.social/tags/Merz" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Merz</span></a> <a href="https://mastodon.social/tags/S%C3%B6der" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Söder</span></a> <a href="https://mastodon.social/tags/CarmenWegge" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CarmenWegge</span></a> <a href="https://mastodon.social/tags/ACM" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ACM</span></a></p>
JADe (he, him)<p><span class="h-card" translate="no"><a href="https://paquita.masto.host/@Kyol" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>Kyol</span></a></span> </p><p>Hola. Yo hago "marigüanol" para mi madre de 82, que también padece de artrosis. Hace un par de años tuvo una caída y ahora lleva prótesis de titanio en muñeca y tobillo.</p><p>Este ungüento de CBN + CBD le ayuda a dormir sin dolor.</p><p>El Cannabinol (CBN) es activador de receptores CB2, con mayor presencia en hígado, periferia del cuerpo, sistema inmune, piel y huesos. </p><p>El CBD es necesario modulador pero como explica este estudio, el control del dolor (analgesia) es mayor si ambos CBN y CBD están presentes en cantidades parecidas. Cuando domina el CBD el efecto analgésico se reduce. </p><p><a href="https://www.sciencedirect.com/science/article/abs/pii/S0003996919302249" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">sciencedirect.com/science/arti</span><span class="invisible">cle/abs/pii/S0003996919302249</span></a></p><p>Este ungüento se produce al cocer flor "recreativa" equilibrada 1:1 o al menos de tipo indica, en aceite de oliva o aguacate a 90 C por 60 minutos. Una vez cocida pasas esta mezcla por filtros de papel para café. Ya limpia sin materia vegetal la mezclas con una parte igual de manteca de cacao derretida y calientas de nuevo, agitando constantemente hasta emparejar.</p><p>Yo uso 4 gr de flor seca desmenuzada por cada 100 ml de aceite. Los tiempos y temperaturas deben respetarse, pues se basan en la Calculadora de Preservación del Cannabis mezcla, y cambia si en la mezcla domina THCA, THC o CBN, lo que cambia el efecto. </p><p><a href="https://metrology.shinyapps.io/cannabis-calculator/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">metrology.shinyapps.io/cannabi</span><span class="invisible">s-calculator/</span></a></p><p>Pej el THCA que domina en flor "recreativa" cruda no provoca volazón, pero es ansiolítico, neuroprotector, antiespasmódico, antiemético y desinflamante. Razono todas sus propiedades comprobadas y explico su uso como tisana en mi blog:</p><p><a href="https://jorge-alban-dobles.blogspot.com/2023/07/bombo-cannabinoides-acidos-y-longevidad.html?m=1" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jorge-alban-dobles.blogspot.co</span><span class="invisible">m/2023/07/bombo-cannabinoides-acidos-y-longevidad.html?m=1</span></a></p><p>El THC que domina en flor ligeramente tostada o descarboxilada, es el único realmente psicotrópico, pero el más analgésico y anticancerígeno de todos.</p><p>El CBN de la flor cocida, ideal para el ungüento tópico, además de analgésico, es neuroprotector, anti insomnio, destruye superbacterias y atrae células madre de la médula para reparar fracturas y mejorar densidad ósea. </p><p>No venta ni distribución, solo educación sobre el tema.</p><p><a href="https://mastodon.cr/tags/medicinalplant" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medicinalplant</span></a> <a href="https://mastodon.cr/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabis</span></a> <a href="https://mastodon.cr/tags/thc" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>thc</span></a> <a href="https://mastodon.cr/tags/cbd" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbd</span></a> <a href="https://mastodon.cr/tags/cbn" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbn</span></a> <a href="https://mastodon.cr/tags/cannabismedicinal" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabismedicinal</span></a> <a href="https://mastodon.cr/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoid</span></a> <a href="https://mastodon.cr/tags/weed" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>weed</span></a> <a href="https://mastodon.cr/tags/marihuana" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>marihuana</span></a></p>
Karl Theodor<p>Für Anwälte und Anwältinnen und Klagende: Wirklich evidente Informationen kann man da bekommen. Das sind die absoluten Spitzenleute, was die Forschung zu <a href="https://mastodon.social/tags/Cannabinoiden" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoiden</span></a> anbelangt.</p><p><a href="https://cannabis-med.org/de" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">cannabis-med.org/de</span><span class="invisible"></span></a> [deutsch]</p><p><a href="https://cannabis-med.org/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">cannabis-med.org/</span><span class="invisible"></span></a> [english]</p><p>The aim of the International Alliance for <a href="https://mastodon.social/tags/Cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoid</span></a> Medicines (<a href="https://mastodon.social/tags/IACM" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>IACM</span></a>) is to advance knowledge on <a href="https://mastodon.social/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabis</span></a>, <a href="https://mastodon.social/tags/cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoids</span></a>, the <a href="https://mastodon.social/tags/endocannabinoidsystem" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endocannabinoidsystem</span></a> and related topics, especially their therapeutic potential.</p><p><a href="https://mastodon.social/tags/Bayern" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Bayern</span></a> <a href="https://mastodon.social/tags/Cannabisklage" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabisklage</span></a> <a href="https://mastodon.social/tags/Hanfwissen" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Hanfwissen</span></a></p>
Kenny Lenny Kirk<p>Merry Cannabis and Hippy Nude Year💓 <a href="https://bsky.app/search?q=%23canada" rel="nofollow noopener" target="_blank">#canada</a> <a href="https://bsky.app/search?q=%23canabis" rel="nofollow noopener" target="_blank">#canabis</a> <a href="https://bsky.app/search?q=%23THC" rel="nofollow noopener" target="_blank">#THC</a> <a href="https://bsky.app/search?q=%23CBD" rel="nofollow noopener" target="_blank">#CBD</a> <a href="https://bsky.app/search?q=%23Cannabinoid" rel="nofollow noopener" target="_blank">#Cannabinoid</a> <a href="https://bsky.app/search?q=%23legalize" rel="nofollow noopener" target="_blank">#legalize</a> <a href="https://bsky.app/search?q=%23hemp" rel="nofollow noopener" target="_blank">#hemp</a> <a href="https://bsky.app/search?q=%23weed" rel="nofollow noopener" target="_blank">#weed</a> <a href="https://bsky.app/search?q=%23kush" rel="nofollow noopener" target="_blank">#kush</a> <a href="https://bsky.app/search?q=%23endprohibition" rel="nofollow noopener" target="_blank">#endprohibition</a> <a href="https://bsky.app/search?q=%23legalizemarijuana" rel="nofollow noopener" target="_blank">#legalizemarijuana</a> <a href="https://bsky.app/search?q=%23legalizecannabis" rel="nofollow noopener" target="_blank">#legalizecannabis</a> <a href="https://bsky.app/search?q=%23Marijuana" rel="nofollow noopener" target="_blank">#Marijuana</a> <a href="https://bsky.app/search?q=%23MarijuanaParty" rel="nofollow noopener" target="_blank">#MarijuanaParty</a> <a href="https://bsky.app/search?q=%23NDP" rel="nofollow noopener" target="_blank">#NDP</a> <a href="https://bsky.app/search?q=%23YEG" rel="nofollow noopener" target="_blank">#YEG</a> <a href="https://bsky.app/search?q=%23Solidarity" rel="nofollow noopener" target="_blank">#Solidarity</a> <a href="https://bsky.app/search?q=%23Liberal" rel="nofollow noopener" target="_blank">#Liberal</a> <a href="https://bsky.app/search?q=%23Trudeau" rel="nofollow noopener" target="_blank">#Trudeau</a> <a href="https://bsky.app/search?q=%23Politics" rel="nofollow noopener" target="_blank">#Politics</a> <a href="https://bsky.app/search?q=%23prohibition" rel="nofollow noopener" target="_blank">#prohibition</a> <a href="https://bsky.app/search?q=%23Democracy" rel="nofollow noopener" target="_blank">#Democracy</a> <a href="https://bsky.app/search?q=%23CDNpoli" rel="nofollow noopener" target="_blank">#CDNpoli</a> <a href="https://bsky.app/search?q=%23CanPoli" rel="nofollow noopener" target="_blank">#CanPoli</a> <a href="https://bsky.app/search?q=%23ABpoli" rel="nofollow noopener" target="_blank">#ABpoli</a> <a href="https://bsky.app/search?q=%23ABleg" rel="nofollow noopener" target="_blank">#ABleg</a> <a href="https://bsky.app/search?q=%23CPC" rel="nofollow noopener" target="_blank">#CPC</a> <a href="https://bsky.app/search?q=%23LPC" rel="nofollow noopener" target="_blank">#LPC</a></p>
Karl Theodor<p><span class="h-card" translate="no"><a href="https://mastodon.social/@topgras" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>topgras</span></a></span> wirklich evidente Informationen kann man da bekommen. Das sind die absoluten Spitzenleute, was die Forschung zu <a href="https://mastodon.social/tags/Cannabinoiden" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoiden</span></a> anbelangt.</p><p><a href="https://cannabis-med.org/de" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">cannabis-med.org/de</span><span class="invisible"></span></a> [deutsch]</p><p><a href="https://cannabis-med.org/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">cannabis-med.org/</span><span class="invisible"></span></a> [english]</p><p>The aim of the International Alliance for <a href="https://mastodon.social/tags/Cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoid</span></a> Medicines (<a href="https://mastodon.social/tags/IACM" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>IACM</span></a>) is to advance knowledge on <a href="https://mastodon.social/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabis</span></a>, <a href="https://mastodon.social/tags/cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoids</span></a>, the <a href="https://mastodon.social/tags/endocannabinoidsystem" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endocannabinoidsystem</span></a> and related topics, especially their therapeutic potential.</p><p><a href="https://mastodon.social/tags/Hanf" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Hanf</span></a> <a href="https://mastodon.social/tags/Weed" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Weed</span></a> <a href="https://mastodon.social/tags/Wissenschaft" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Wissenschaft</span></a> <a href="https://mastodon.social/tags/Medizin" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Medizin</span></a> <a href="https://mastodon.social/tags/Wissen" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Wissen</span></a> <a href="https://mastodon.social/tags/Evidenz" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Evidenz</span></a> <a href="https://mastodon.social/tags/Marijuana" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Marijuana</span></a></p>
Manni_P :mastolove:<p><span class="h-card" translate="no"><a href="https://mastodon.world/@formuchdeliberation" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>formuchdeliberation</span></a></span> Die Allianz für <a href="https://troet.cafe/tags/Cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoid</span></a>-<a href="https://troet.cafe/tags/Medikamente" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Medikamente</span></a><br>Wissen über <a href="https://troet.cafe/tags/Cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabis</span></a>, <a href="https://troet.cafe/tags/Cannabinoide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoide</span></a>, das <a href="https://troet.cafe/tags/Endocannabinoidsystem" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Endocannabinoidsystem</span></a> und verwandte Themen zu fördern, insbesondere im Hinblick auf ihr therapeutisches Potenzial.</p><p>Unterstützung der <a href="https://troet.cafe/tags/Forschung" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Forschung</span></a> über <br>Cannabis und Endocannabinoidsystem<br><a href="https://troet.cafe/tags/Cannabisprodukte" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabisprodukte</span></a> ..</p><p>Förderung des <a href="https://troet.cafe/tags/Informationsaustausch" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Informationsaustausch</span></a>:s Gesundheitsberufe, Patienten und der Öffentlichkeit ...<br>🚻 🔋 👯 <a href="https://cannabis-med.org/de" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">cannabis-med.org/de</span><span class="invisible"></span></a> <a href="https://troet.cafe/tags/IACM" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>IACM</span></a> <a href="https://troet.cafe/tags/WEEDMoB" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>WEEDMoB</span></a> <a href="https://troet.cafe/tags/Hanf" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Hanf</span></a> <a href="https://troet.cafe/tags/Medizin" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Medizin</span></a> <a href="https://troet.cafe/tags/KamalaHarris" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>KamalaHarris</span></a> <a href="https://troet.cafe/tags/USA" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>USA</span></a> <a href="https://troet.cafe/tags/Germany" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Germany</span></a> 💚</p>
nemo™ 🇺🇦<p><a href="https://mas.to/tags/Synthetic" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Synthetic</span></a> <a href="https://mas.to/tags/Biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Biology</span></a>: The Next Step in the <a href="https://mas.to/tags/Cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoid</span></a> Revolution</p><p><a href="https://www.labiotech.eu/in-depth/cannabinoid-synthetic-biology/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">labiotech.eu/in-depth/cannabin</span><span class="invisible">oid-synthetic-biology/</span></a></p><p><a href="https://mas.to/tags/nemoradio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>nemoradio</span></a></p>
DoomsdaysCW<p><a href="https://kolektiva.social/tags/Cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoids</span></a> as novel <a href="https://kolektiva.social/tags/AntiInflammatory" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>AntiInflammatory</span></a> drugs</p><p>by Prakash Nagarkatti, et al.<br>October, 2009</p><p>Abstract:</p><p>"Cannabinoids are a group of compounds that mediate their effects through cannabinoid receptors. The discovery of Δ9-tetrahydrocannabinol (<a href="https://kolektiva.social/tags/THC" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>THC</span></a>) as the major psychoactive principle in marijuana, as well as the identification of <a href="https://kolektiva.social/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoid</span></a> receptors and their endogenous ligands, has led to a significant growth in research aimed at understanding the physiological functions of cannabinoids. Cannabinoid receptors include CB1, which is predominantly expressed in the brain, and CB2, which is primarily found on the cells of the immune system. The fact that both CB1 and CB2 receptors have been found on <a href="https://kolektiva.social/tags/immune" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>immune</span></a> cells suggests that cannabinoids play an important role in the regulation of the immune system. Recent studies demonstrated that administration of THC into mice triggered marked apoptosis in T cells and dendritic cells, resulting in immunosuppression. In addition, several studies showed that cannabinoids downregulate <a href="https://kolektiva.social/tags/cytokine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cytokine</span></a> and chemokine production and, in some models, upregulate T-regulatory cells (Tregs) as a mechanism to suppress <a href="https://kolektiva.social/tags/inflammatory" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>inflammatory</span></a> responses. The <a href="https://kolektiva.social/tags/endocannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endocannabinoid</span></a> system is also involved in <a href="https://kolektiva.social/tags/immunoregulation" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>immunoregulation</span></a>. For example, administration of endocannabinoids or use of inhibitors of enzymes that break down the endocannabinoids, led to immunosuppression and recovery from immune-mediated injury to organs such as the liver. Manipulation of endocannabinoids and/or use of exogenous cannabinoids in vivo can constitute a potent treatment modality against inflammatory disorders. This review will focus on the potential use of cannabinoids as a new class of anti-inflammatory agents against a number of inflammatory and autoimmune diseases that are primarily triggered by activated T cells or other cellular immune components."</p><p>Executive summary</p><p>- Cannabinoids, the active components of <a href="https://kolektiva.social/tags/CannabisSativa" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CannabisSativa</span></a>, and endogenous cannabinoids mediate their effects through activation of specific cannabinoid receptors known as cannabinoid receptor 1 and 2 (CB1 and CB2).</p><p>- The cannabinoid system has been shown both in vivo and in vitro to be involved in regulating the immune system through its immunomodulatory properties.</p><p>- Cannabinoids suppress inflammatory response and subsequently attenuate disease symptoms. This property of cannabinoids is mediated through multiple pathways such as induction of apoptosis in activated immune cells, suppression of cytokines and chemokines at inflammatory sites and upregulation of FoxP3+ regulatory T cells.</p><p>- Cannabinoids have been tested in several experimental models of autoimmune disorders such as <a href="https://kolektiva.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a>, <a href="https://kolektiva.social/tags/RheumatoidArthritis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>RheumatoidArthritis</span></a>, <a href="https://kolektiva.social/tags/colitis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>colitis</span></a> and <a href="https://kolektiva.social/tags/hepatitis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hepatitis</span></a> and have been shown to protect the host from the pathogenesis through induction of multiple anti-inflammatory pathways.</p><p>- Cannabinoids may also be beneficial in certain types of <a href="https://kolektiva.social/tags/cancers" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cancers</span></a> that are triggered by <a href="https://kolektiva.social/tags/ChronicInflammation" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ChronicInflammation</span></a> In such instances, cannabinoids can either directly inhibit tumor growth or suppress inflammation and tumor angiogenesis.</p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">ncbi.nlm.nih.gov/pmc/articles/</span><span class="invisible">PMC2828614/</span></a></p>
Getzler Lab at KenyonCollege<p>Reading a student capstone paper about synthetic <a href="https://mstdn.science/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoid</span></a> receptor agonists and the author notes that "Efficacy can also be determined in vivo by radiobiotelemmetry, which can quantify physiological levels of the 'cannabinoid tetrad' (i.e. hypothermia, analgesia, hypolocomotion, and catalepsy)." This has got to be the most sciency way ever of saying that you can tell if the person is really high. <a href="https://mstdn.science/tags/chemistry" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>chemistry</span></a> <a href="https://mstdn.science/tags/proflife" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>proflife</span></a></p>
Matt Willemsen<p>“People Have To Be Careful” – Scientists Debunk Claims of a Psychedelic Cannabinoid<br>Despite increasing popularity and claims about its psychedelic effects similar to LSD or psilocybin mushrooms, THC-O-acetate, a cannabinoid derived from delta-8 THC, doesn’t induce significant psychedelic experiences, according to a recent study. THC-O-acetate due to its acetate composition, when heated can produce toxic gas.<br><a href="https://scitechdaily.com/people-have-to-be-careful-scientists-debunk-claims-of-a-psychedelic-cannabinoid/" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="ellipsis">scitechdaily.com/people-have-t</span><span class="invisible">o-be-careful-scientists-debunk-claims-of-a-psychedelic-cannabinoid/</span></a> <a href="https://fedibird.com/tags/Psychedelic" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Psychedelic</span></a> <a href="https://fedibird.com/tags/Cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoid</span></a> <a href="https://fedibird.com/tags/toxic" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>toxic</span></a> <a href="https://fedibird.com/tags/gas" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>gas</span></a></p>
AutisticMumTo3 She/her<p>Worms crave junk food after consuming cannabis, study suggests | Cannabis | The Guardian<br><a href="https://mastodon.uk.com/tags/Cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabis</span></a><br><a href="https://mastodon.uk.com/tags/JunkFood" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>JunkFood</span></a><br><a href="https://mastodon.uk.com/tags/HighCalorieFoods" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>HighCalorieFoods</span></a><br><a href="https://mastodon.uk.com/tags/Cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoid</span></a><br><a href="https://mastodon.uk.com/tags/THC" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>THC</span></a><br><a href="https://mastodon.uk.com/tags/EndocannabinoidSystem" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>EndocannabinoidSystem</span></a><br><a href="https://mastodon.uk.com/tags/Worms" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Worms</span></a><br><a href="https://mastodon.uk.com/tags/Humans" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Humans</span></a><br> <a href="https://www.theguardian.com/society/2023/apr/20/worms-crave-junk-food-after-consuming-cannabis-study-suggests" rel="nofollow noopener" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">theguardian.com/society/2023/a</span><span class="invisible">pr/20/worms-crave-junk-food-after-consuming-cannabis-study-suggests</span></a></p>
Scientific Frontline<p>High levels of the body’s own <a href="https://mastodon.social/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoid</span></a> substances protect against developing <a href="https://mastodon.social/tags/addiction" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>addiction</span></a> in individuals previously exposed to childhood <a href="https://mastodon.social/tags/maltreatment" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>maltreatment</span></a>, according to a new study. Those who had not developed an addiction following childhood maltreatment seem to process emotion-related social signals better.<br><a href="https://mastodon.social/tags/Neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neuroscience</span></a> <a href="https://mastodon.social/tags/Psychiatry" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Psychiatry</span></a> <a href="https://mastodon.social/tags/sflorg" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>sflorg</span></a><br><a href="https://www.sflorg.com/2023/04/ns04122301.html" rel="nofollow noopener" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">sflorg.com/2023/04/ns04122301.</span><span class="invisible">html</span></a></p>
Anna<p><a href="https://disabled.social/tags/Pain" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Pain</span></a> advice please? </p><p>Is <a href="https://disabled.social/tags/marijuana" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>marijuana</span></a> good for weaning off <a href="https://disabled.social/tags/opiates" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>opiates</span></a>? Is it a replacement? Whole plant or <a href="https://disabled.social/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoid</span></a> fractions? I don’t think <a href="https://disabled.social/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CBD</span></a> on its own could do it.</p><p>Is <a href="https://disabled.social/tags/LDN" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>LDN</span></a> compatible with MJ products? </p><p>What are my options?</p><p>I’ve long term pain that isn’t going away but I don’t want to be on opiates forever, &amp; if Australia goes the same way as the USA in legislating painkillers, I won’t have a choice anyway.</p><p><a href="https://disabled.social/tags/ChronicPain" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ChronicPain</span></a> <a href="https://disabled.social/tags/Migraine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Migraine</span></a> <a href="https://disabled.social/tags/Endometriosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Endometriosis</span></a> <a href="https://disabled.social/tags/MECFS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MECFS</span></a> <br><span class="h-card"><a href="https://a.gup.pe/u/chronicpain" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>chronicpain</span></a></span><br><span class="h-card"><a href="https://a.gup.pe/u/chronicillness" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>chronicillness</span></a></span></p>
NicholasRChronic pain, drug (prescription & non) mention
Scientific Frontline<p>In <a href="https://mastodon.social/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabis</span></a> trials against <a href="https://mastodon.social/tags/pain" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pain</span></a>, people who take <a href="https://mastodon.social/tags/placebos" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>placebos</span></a> report feeling largely the same level of pain relief as those who consume the active <a href="https://mastodon.social/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoid</span></a> substance. <br><a href="https://mastodon.social/tags/Medical" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Medical</span></a> <a href="https://mastodon.social/tags/Pharmaceutical" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Pharmaceutical</span></a> <a href="https://mastodon.social/tags/sflorg" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>sflorg</span></a><br><a href="https://www.sflorg.com/2022/11/med11282202.html" rel="nofollow noopener" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">sflorg.com/2022/11/med11282202</span><span class="invisible">.html</span></a></p>
Anna<p>Wrote this when less <a href="https://aus.social/tags/PEM" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PEM</span></a> crashed, but could be a typo/ comprehension minefield:</p><p>Does anyone know if <a href="https://aus.social/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CBD</span></a> oil interferes with <a href="https://aus.social/tags/oestrogen" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>oestrogen</span></a>? In general but specifically the <a href="https://aus.social/tags/OCP" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>OCP</span></a> (oral contraceptive pill).</p><p>Would I be better off consuming the whole plant? Perhaps oil from the whole plant? Has anyone had personal experience?</p><p>There is some good evidence that <a href="https://aus.social/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabis</span></a> can stop <a href="https://aus.social/tags/endometriosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endometriosis</span></a> from growing outside the uterus altogether, so I’m looking at this as a form of <a href="https://aus.social/tags/pain" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pain</span></a> relief as well as a treatment and preventative. I don’t know which form and dose is best though.</p><p>The only other treatment for endometriosis is more hormones (which make me sick) and surgery, after which it grows back. Can’t find a doctor specialising in alternative treatments. They all just want to give you a <a href="https://aus.social/tags/Mirena" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Mirena</span></a> <a href="https://aus.social/tags/IUD" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>IUD</span></a> (without anaesthetic!) and surgery after surgery. Sometimes <a href="https://aus.social/tags/hysterectomy" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hysterectomy</span></a> if bad enough. <br> <br>There’s also been some studies about CBD oil and <a href="https://aus.social/tags/LongCovid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>LongCovid</span></a>. Something about switching on the <a href="https://aus.social/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoid</span></a> system.</p><p>Disclaimer: Yes of course I would get a <a href="https://aus.social/tags/medical" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medical</span></a> <a href="https://aus.social/tags/marijuana" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>marijuana</span></a> license and buy it legally on prescription.<br>*cough*</p>
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