#Efficacy of late-onset #antiviral #treatment in immunocompromised hosts with persistent #SARS-CoV-2 infection, J Virol.: https://journals.asm.org/doi/full/10.1128/jvi.00905-24?af=R

These data indicate that late-onset DAA therapy significantly shortens #duration of persistent virus #replication in an immunocompromised host, which may have implications for clinical use of antiviral therapeutics to alleviate the risk of progression to severe disease in highly vulnerable patients.

[US] #FDA #Research #Agenda for 2024 Highly Pathogenic #H5N1 Avian #Influenza, https://www.fda.gov/media/179559/download?attachment

Investigating #temperature thresholds and #duration required to effectively neutralize #H5N1 HPAI virus is necessary to better understand #inactivation methods. FDA is working on multiple efforts to understand the effectiveness of #pasteurization and other inactivation methods.

#Duration of #fever in #children infected with #influenza #H1N1pdm09, #H3N2 or B virus & treated with #baloxavir, #oseltamivir, #laninamivir, or #zanamivir in #Japan during the 2012–13 & 2019–20 seasons, Antiviral Res.: https://www.sciencedirect.com/science/article/pii/S0166354224001475?via%3Dihub

We compared fever duration between baloxavir- & 3 NAIs-treated groups. ...For influenza A, fever duration in baloxavir- & NAIs-treated groups was similar. For influenza B, fever duration was ∼15 h shorter in baloxavir-treated group.

#愛出發. and no. still no #flyingpants. #privatejoke

but #freeasabird?!!… maybe it’s time for me to think of a new #saying to represent my #stateofmind when i #travel in the future.

this another #lastminute #nonplan of mine is probably the #craziest in terms of #duration… lemme not focus on that too much and i will then tell you whether it’s #crazy or not when it’s done.

Well designed information is clear, unambiguous, and enhances comprehension and other human performance.

The illustration below shows a duration. Several design changes could each have made this usable, such as adding a space:
23:00 09:30
or a word:
23:00 to 09:30

Survival Declines Rapidly With Longer Duration of CPR
https://www.medscape.com/viewarticle/survival-declines-rapidly-longer-duration-cpr-2024a10002yz?src=rss&form=fpf #health #CPR #survival #duration #NeurologicOutcome #resuscitation #CardiacArrest

#Isolation may select for earlier and higher #peak viral load but shorter #duration in #SARS-CoV-2 #evolution https://www.nature.com/articles/s41467-023-43043-2

Inktober day 22
SCRATCHY

“Like how the winged creature, in her transitional state, defaces contiguous time and becomes duration.”

Diabetes Duration Linked to Alarming Brain Structure Changes
A Michigan Medicine study found that the longer an individual has type 2 diabetes, the more likely they are to exhibit changes in brain structure, such as decreased cortical thickness and gray matter volumes. Despite no discernible difference in cognition between those with and without diabetes, complications like chronic kidney disease and vascular damage in diabetes are linked to these brain changes.
https://scitechdaily.com/diabetes-duration-linked-to-alarming-brain-structure-changes/?expand_article=1 #T2D #diabetes #duration #brain #structure #CorticalThickness

Crunched the numbers to see the impact of baseball's rule changes on game lengths.

• Games are 35 mins shorter than 2021 peak.

• Cardinals' avg of 159.1 mins is just a hair above the MLB avg.

• Cardinals played in 2nd-longest 9-inning game this year.

https://www.stltoday.com/sports/baseball/professional/baseball-has-picked-up-the-pace-in-2023-data-shows/article_7bd08ee0-e795-11ed-84db-1b53aeda9d87.html

ZIRP for a decade led to:
- VCs FA’ing, but never FO’ing
- boom in solutions to non-existent problems (i.e. crypto)
- concentration in commercial real estate, rather than housing

The mismatch of risks, durations, and sensitivity to interest rates takes down SVB, Republic, and Signature.

Next domino to fall as a result of 10+ years of artificially boosted economy…?