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#inflammatory

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Nonilex<p><a href="https://masto.ai/tags/Trump" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Trump</span></a> signed a memo late on Saturday ordering 2,000 <a href="https://masto.ai/tags/NationalGuard" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>NationalGuard</span></a> members to be deployed in <a href="https://masto.ai/tags/LosAngeles" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LosAngeles</span></a> County after federal <a href="https://masto.ai/tags/immigration" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immigration</span></a> agents in riot gear squared off w/hundreds of <a href="https://masto.ai/tags/protesters" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>protesters</span></a> for a 2nd consecutive, the WH propagandist said.<br>Gov. <a href="https://masto.ai/tags/GavinNewsom" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>GavinNewsom</span></a> confirmed the call-up. “The federal government is moving to take over the California National Guard &amp; deploy 2,000 <a href="https://masto.ai/tags/soldiers" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>soldiers</span></a>,”he said in a stmnt. “That move is purposefully <a href="https://masto.ai/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> &amp; will only <a href="https://masto.ai/tags/escalate" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>escalate</span></a> tensions.”<br><a href="https://masto.ai/tags/law" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>law</span></a> <a href="https://masto.ai/tags/democracy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>democracy</span></a></p>
divVerent<p>Facts about <a href="https://social.vivaldi.net/tags/TerahertzRadiation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>TerahertzRadiation</span></a> (1/2)</p><p>- By Terahertz Radiation we understand radio waves in the range from about 100 to 1000 THz.</p><p>- Terahertz Radiation is known to cause an <a href="https://social.vivaldi.net/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> reaction on the skin which in some cases can lead to skin <a href="https://social.vivaldi.net/tags/cancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cancer</span></a>.</p><p>- Excessive exposure to Terahertz Radiation can cause permanent eye damage and blindness. It happens frequently around <a href="https://social.vivaldi.net/tags/solar" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>solar</span></a> <a href="https://social.vivaldi.net/tags/eclipses" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>eclipses</span></a>.</p><p>- Terahertz Radiation is primarily created in nuclear <a href="https://social.vivaldi.net/tags/fusion" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>fusion</span></a> reactors. Most of us live within 8 minutes of a Terahertz Radiation emitting reactor.</p><p>- The surface of such a Terahertz Radiation emitting <a href="https://social.vivaldi.net/tags/reactor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>reactor</span></a> is actually so hot that your whole body would burn up instantly if you were to touch it.</p><p>- Due to the immense danger it poses to humans and the environment, the <a href="https://social.vivaldi.net/tags/European" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>European</span></a> Union and the state of <a href="https://social.vivaldi.net/tags/California" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>California</span></a> have actually banned the sale of a, sadly, commonly deployed device emitting Terahertz Radiation.</p><p>- Pulsed Terahertz Radiation is a common cause of <a href="https://social.vivaldi.net/tags/headaches" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>headaches</span></a> in humans and animals, and can in some causes even lead to grand mal <a href="https://social.vivaldi.net/tags/seizures" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>seizures</span></a>.</p><p>- Terahertz Radiation is known to cause <a href="https://social.vivaldi.net/tags/wildfires" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>wildfires</span></a> </p><p>- The Ancient <a href="https://social.vivaldi.net/tags/Greek" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Greek</span></a> are said to have already used Terahertz Radiation to fight off their enemies.</p><p><a href="https://social.vivaldi.net/tags/conspiracy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>conspiracy</span></a></p>
philjreese<p>Itching Solution: New Approach Could Treat <a href="https://mstdn.party/tags/Inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Inflammatory</span></a> Skin Conditions Like <a href="https://mstdn.party/tags/Eczema" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Eczema</span></a> with ‘Huge Benefits’</p><p><a href="https://mstdn.party/tags/Science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Science</span></a> </p><p><a href="https://www.goodnewsnetwork.org/itching-solution-new-approach-could-treat-inflammatory-skin-conditions-like-eczema-with-huge-benefits/" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">goodnewsnetwork.org/itching-so</span><span class="invisible">lution-new-approach-could-treat-inflammatory-skin-conditions-like-eczema-with-huge-benefits/</span></a></p><p>&gt; A daily cream containing a GluK2-activating compound could therefore be a promising way to prevent several inflammatory skin conditions.</p>
Susan Larson ♀️🏳️‍🌈🏳️‍⚧️🌈<p><a href="https://mastodon.online/tags/GeraldoRivera" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>GeraldoRivera</span></a> Goes OFF At <a href="https://mastodon.online/tags/MAGA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MAGA</span></a> <a href="https://mastodon.online/tags/Speaker" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Speaker</span></a>’s <a href="https://mastodon.online/tags/Insults" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Insults</span></a> To <a href="https://mastodon.online/tags/Hispanic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Hispanic</span></a> <a href="https://mastodon.online/tags/Voters" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Voters</span></a> at <a href="https://mastodon.online/tags/Trump" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Trump</span></a> <a href="https://mastodon.online/tags/MadisonSquareGarden" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MadisonSquareGarden</span></a> <a href="https://mastodon.online/tags/Rally" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Rally</span></a> </p><p><a href="https://mastodon.online/tags/Comedian" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Comedian</span></a> <a href="https://mastodon.online/tags/TonyHinchcliffe" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>TonyHinchcliffe</span></a> led with a <a href="https://mastodon.online/tags/controversial" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>controversial</span></a> <a href="https://mastodon.online/tags/opening" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>opening</span></a> with <a href="https://mastodon.online/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> <a href="https://mastodon.online/tags/jokes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>jokes</span></a> about <a href="https://mastodon.online/tags/PuertoRico" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PuertoRico</span></a>, as “a floating <a href="https://mastodon.online/tags/island" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>island</span></a> of <a href="https://mastodon.online/tags/garbage" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>garbage</span></a>.” </p><p>Trump's <a href="https://mastodon.online/tags/campaign" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>campaign</span></a> <a href="https://mastodon.online/tags/distanced" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>distanced</span></a> themselves from the <a href="https://mastodon.online/tags/remarks" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>remarks</span></a>, saying the <a href="https://mastodon.online/tags/views" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>views</span></a> do not represent those of <a href="https://mastodon.online/tags/DonaldTrump" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>DonaldTrump</span></a>. </p><p>— Except He read his <a href="https://mastodon.online/tags/speech" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>speech</span></a> off of a <a href="https://mastodon.online/tags/teleprompter" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>teleprompter</span></a>. Which means they knew in advance.</p><p><a href="https://www.mediaite.com/news/fck-these-racists-geraldo-rivera-goes-off-at-maga-speakers-insults-to-hispanic-voters-at-trump-msg-rally/" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">mediaite.com/news/fck-these-ra</span><span class="invisible">cists-geraldo-rivera-goes-off-at-maga-speakers-insults-to-hispanic-voters-at-trump-msg-rally/</span></a></p>
Susan Larson ♀️🏳️‍🌈🏳️‍⚧️🌈<p>A <a href="https://mastodon.online/tags/century" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>century</span></a> of <a href="https://mastodon.online/tags/JamesBaldwin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>JamesBaldwin</span></a>’s <a href="https://mastodon.online/tags/prophetic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>prophetic</span></a> <a href="https://mastodon.online/tags/voice" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>voice</span></a>. </p><p>This <a href="https://mastodon.online/tags/essay" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>essay</span></a> uses an <a href="https://mastodon.online/tags/offensive" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>offensive</span></a> <a href="https://mastodon.online/tags/racial" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>racial</span></a> <a href="https://mastodon.online/tags/epithet" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>epithet</span></a> in <a href="https://mastodon.online/tags/citing" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>citing</span></a> <a href="https://mastodon.online/tags/JamesBaldwin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>JamesBaldwin</span></a>’s <a href="https://mastodon.online/tags/work" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>work</span></a>. I choose to use it to underscore the important <a href="https://mastodon.online/tags/insight" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>insight</span></a> that Baldwin meant to convey by using this <a href="https://mastodon.online/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> <a href="https://mastodon.online/tags/term" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>term</span></a>. </p><p><a href="https://mastodon.online/tags/Women" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Women</span></a> <a href="https://mastodon.online/tags/Transgender" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Transgender</span></a> <a href="https://mastodon.online/tags/LGBTQ" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LGBTQ</span></a> <a href="https://mastodon.online/tags/LGBTQIA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LGBTQIA</span></a> <a href="https://mastodon.online/tags/Entertainment" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Entertainment</span></a> <a href="https://mastodon.online/tags/TheArts" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>TheArts</span></a> <a href="https://mastodon.online/tags/Literature" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Literature</span></a> <a href="https://mastodon.online/tags/Books" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Books</span></a> <a href="https://mastodon.online/tags/Reading" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Reading</span></a> <a href="https://mastodon.online/tags/Representation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Representation</span></a> <a href="https://mastodon.online/tags/Culture" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Culture</span></a> <a href="https://mastodon.online/tags/RoleModels" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>RoleModels</span></a> <a href="https://mastodon.online/tags/BlackMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>BlackMastodon</span></a> </p><p><a href="https://www.americamagazine.org/faith/2024/09/23/james-baldwin-centenary-massingale-248835" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">americamagazine.org/faith/2024</span><span class="invisible">/09/23/james-baldwin-centenary-massingale-248835</span></a></p>
Geriatric Gardener<p>“Southport imam tells the Canary about the far-right riot and the real situation in the town”</p><p>by Ed Sykes in The Canary <span class="h-card" translate="no"><a href="https://mspsocial.net/@thecanary" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>thecanary</span></a></span> <span class="h-card" translate="no"><a href="https://mastodon.cloud/@UKLabour" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>UKLabour</span></a></span></p><p>Imam Ibrahim Hussein said: “Why be an enemy? Life is too short. You do not need to create an enemy from somebody that you don’t even know anything about. These people [the Far Right] who came here, they hate everything around them.”</p><p><a href="https://www.thecanary.co/uk/analysis/2024/09/19/southport-imam-riots/?__s=pw3ygmyxve9etudpqdrh" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">thecanary.co/uk/analysis/2024/</span><span class="invisible">09/19/southport-imam-riots/?__s=pw3ygmyxve9etudpqdrh</span></a></p><p><a href="https://mstdn.social/tags/Southport" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Southport</span></a> <a href="https://mstdn.social/tags/Riots" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Riots</span></a> <a href="https://mstdn.social/tags/FarRight" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>FarRight</span></a> <a href="https://mstdn.social/tags/Government" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Government</span></a> <a href="https://mstdn.social/tags/Ministers" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Ministers</span></a> <a href="https://mstdn.social/tags/Inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Inflammatory</span></a> <a href="https://mstdn.social/tags/Language" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Language</span></a> <a href="https://mstdn.social/tags/Racism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Racism</span></a> <a href="https://mstdn.social/tags/Tory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Tory</span></a> <a href="https://mstdn.social/tags/Labour" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Labour</span></a></p>
Steve Dustcircle 🌹<p>The association of <a href="https://masto.ai/tags/dietary" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>dietary</span></a> <a href="https://masto.ai/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> <a href="https://masto.ai/tags/indices" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>indices</span></a> and <a href="https://masto.ai/tags/mortality" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>mortality</span></a> in <a href="https://masto.ai/tags/patients" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>patients</span></a> with <a href="https://masto.ai/tags/cirrhosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cirrhosis</span></a>: a cohort based study</p><p><a href="https://www.nature.com/articles/s41598-024-72485-x" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s41598-024</span><span class="invisible">-72485-x</span></a></p>
Susan Larson ♀️🏳️‍🌈🏳️‍⚧️🌈<p><a href="https://mastodon.online/tags/ConvictedFelon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ConvictedFelon</span></a> <a href="https://mastodon.online/tags/DonaldTrump" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>DonaldTrump</span></a> <a href="https://mastodon.online/tags/Slammed" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Slammed</span></a> After New ‘<a href="https://mastodon.online/tags/Inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Inflammatory</span></a>’ <a href="https://mastodon.online/tags/AllCaps" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>AllCaps</span></a> <a href="https://mastodon.online/tags/Claim" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Claim</span></a> About <a href="https://mastodon.online/tags/DemocraticParty" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>DemocraticParty</span></a> <a href="https://mastodon.online/tags/PresidentialNominee" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PresidentialNominee</span></a> <a href="https://mastodon.online/tags/KamalaHarris" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>KamalaHarris</span></a>. </p><p><a href="https://mastodon.online/tags/Trump" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Trump</span></a> and <a href="https://mastodon.online/tags/runningmate" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>runningmate</span></a> <a href="https://mastodon.online/tags/ShadyVance" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ShadyVance</span></a> (<a href="https://mastodon.online/tags/JDVance" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>JDVance</span></a>) have come under increasing <a href="https://mastodon.online/tags/scrutiny" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>scrutiny</span></a> in recent days for pushing <a href="https://mastodon.online/tags/baseless" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>baseless</span></a> <a href="https://mastodon.online/tags/claims" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>claims</span></a> that <a href="https://mastodon.online/tags/Haitian" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Haitian</span></a> <a href="https://mastodon.online/tags/migrants" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>migrants</span></a> in <a href="https://mastodon.online/tags/Springfield" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Springfield</span></a>, <a href="https://mastodon.online/tags/Ohio" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Ohio</span></a>, are <a href="https://mastodon.online/tags/eating" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>eating</span></a> residents’ <a href="https://mastodon.online/tags/pets" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>pets</span></a>.</p><p><a href="https://www.huffpost.com/entry/donald-trump-new-attack-on-kamala-harris_n_66e920b7e4b06998fbecbf72" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">huffpost.com/entry/donald-trum</span><span class="invisible">p-new-attack-on-kamala-harris_n_66e920b7e4b06998fbecbf72</span></a></p>
Giuseppe Michieli<p><a href="https://mstdn.science/tags/SARS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SARS</span></a>-CoV-2 <a href="https://mstdn.science/tags/infection" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>infection</span></a> perturbs the <a href="https://mstdn.science/tags/gastrointestinal" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>gastrointestinal</span></a> tract and induces modest <a href="https://mstdn.science/tags/microbial" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>microbial</span></a> <a href="https://mstdn.science/tags/translocation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>translocation</span></a> across the intestinal barrier, J Virol.: <a href="https://journals.asm.org/doi/abs/10.1128/jvi.01288-24?af=R" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">journals.asm.org/doi/abs/10.11</span><span class="invisible">28/jvi.01288-24?af=R</span></a> </p><p>These results demonstrate that GI perturbations such as microbial translocation can occur in even mild SARS-CoV-2 infections and may contribute to the <a href="https://mstdn.science/tags/COVID19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID19</span></a> <a href="https://mstdn.science/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> state.</p>
Nonilex<p>…As…[the <a href="https://masto.ai/tags/Arlington" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Arlington</span></a>] saga unfolded Tues, Trump’s interview w/ <a href="https://masto.ai/tags/DrPhil" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>DrPhil</span></a> aired. The friendly conversation <a href="https://masto.ai/tags/Trump" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Trump</span></a> filmed last week turned into another venue for him to air <a href="https://masto.ai/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> claims about his opponents w/o evidence. “I think to a certain extent it’s <a href="https://masto.ai/tags/Biden" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Biden</span></a>’s fault &amp; <a href="https://masto.ai/tags/Harris" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Harris</span></a>’s fault,” he said of the attempted assassination…, adding, “They weren’t too interested in my health &amp; safety.” There is NO <a href="https://masto.ai/tags/evidence" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>evidence</span></a> that Biden or Harris were personally involved in decisions about Trump’s security.</p>
PLOS Biology<p>During chronic <a href="https://fediscience.org/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> diseases, how are neutrophils recruited to inflamed <a href="https://fediscience.org/tags/skin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>skin</span></a>? @PierreCoulombe8 @parentclab &amp;co show that repeated acute stress to the skin amplifies a <a href="https://fediscience.org/tags/neutrophil" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>neutrophil</span></a> infiltration response involving keratin 17 &amp; PKCα <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PLOSBiology</span></a> <a href="https://plos.io/3WVA62O" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="">plos.io/3WVA62O</span><span class="invisible"></span></a></p>
Nonilex<p>James Davison Hunter is the distinguished UVA <a href="https://masto.ai/tags/sociologist" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>sociologist</span></a> whose 1991 vol “<a href="https://masto.ai/tags/CultureWars" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CultureWars</span></a>” first brought that term to wide attention. His fascinating new book, “<a href="https://masto.ai/tags/Democracy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Democracy</span></a> &amp; <a href="https://masto.ai/tags/Solidarity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Solidarity</span></a>,” includes an observation essential not only to rebuilding the solidarity he rightly thinks we need but also to <a href="https://masto.ai/tags/understanding" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>understanding</span></a> what’s going on in the 2024 campaign. “It is critical,” Hunter writes, “that we rediscover <a href="https://masto.ai/tags/HumanBeings" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>HumanBeings</span></a> underneath the abstractions of our <a href="https://masto.ai/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> symbolic <a href="https://masto.ai/tags/politics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>politics</span></a>.”<br><a href="https://masto.ai/tags/HarrisWalz2024" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>HarrisWalz2024</span></a></p>
Giuseppe Michieli<p>A <a href="https://mstdn.science/tags/therapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>therapy</span></a> for suppressing canonical &amp; noncanonical <a href="https://mstdn.science/tags/SARS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SARS</span></a>-CoV-2 viral <a href="https://mstdn.science/tags/entry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>entry</span></a> &amp; an intrinsic intrapulmonary <a href="https://mstdn.science/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> response, Proc Natl Acad Sci USA: <a href="https://www.pnas.org/doi/abs/10.1073/pnas.2408109121?af=R" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">pnas.org/doi/abs/10.1073/pnas.</span><span class="invisible">2408109121?af=R</span></a> </p><p>We have harnessed our patient-specific, induced pluripotent stem cell–derived, multicell <a href="https://mstdn.science/tags/lung" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>lung</span></a> <a href="https://mstdn.science/tags/organoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>organoid</span></a> model to investigate critical aspects of <a href="https://mstdn.science/tags/COVID19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID19</span></a>, including viral tropism &amp; routes of entry, lung-specific immune response, &amp; a role for <a href="https://mstdn.science/tags/surfactant" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>surfactant</span></a> protein B in innate immunity...</p>
Nonilex<p>In their own filing, Bragg’s office urged the court to dismiss the appeal, arguing that <a href="https://masto.ai/tags/Trump" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Trump</span></a> has a “well-documented history of leveling <a href="https://masto.ai/tags/threatening" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>threatening</span></a>, <a href="https://masto.ai/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a>, &amp; <a href="https://masto.ai/tags/denigrating" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>denigrating</span></a> remarks against trial participants.”</p><p>Decision:</p><p>“Appeal dismissed without costs, by the Court sua sponte, upon the ground that no substantial constitutional question is directly involved.”</p><p><a href="https://www.nycourts.gov/ctapps/Decisions/2024/Jun24/DecisionList061824.pdf" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nycourts.gov/ctapps/Decisions/</span><span class="invisible">2024/Jun24/DecisionList061824.pdf</span></a> </p><p><a href="https://masto.ai/tags/criminal" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>criminal</span></a> <a href="https://masto.ai/tags/law" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>law</span></a> <a href="https://masto.ai/tags/GagOrder" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>GagOrder</span></a> <a href="https://masto.ai/tags/StochasticTerrorism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>StochasticTerrorism</span></a></p>
Susan Larson ♀️🏳️‍🌈🏳️‍⚧️🌈<p><a href="https://mastodon.online/tags/DonaldTrump" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>DonaldTrump</span></a> <a href="https://mastodon.online/tags/doublesdown" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>doublesdown</span></a> on <a href="https://mastodon.online/tags/racist" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>racist</span></a> <a href="https://mastodon.online/tags/remarks" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>remarks</span></a>, <a href="https://mastodon.online/tags/advocates" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>advocates</span></a> for <a href="https://mastodon.online/tags/white" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>white</span></a> <a href="https://mastodon.online/tags/immigration" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immigration</span></a> <a href="https://mastodon.online/tags/only" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>only</span></a>. </p><p>His <a href="https://mastodon.online/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> <a href="https://mastodon.online/tags/remarks" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>remarks</span></a> suggesting a <a href="https://mastodon.online/tags/preference" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>preference</span></a> for <a href="https://mastodon.online/tags/immigrants" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immigrants</span></a> from <a href="https://mastodon.online/tags/nice" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>nice</span></a> predominantly <a href="https://mastodon.online/tags/white" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>white</span></a> <a href="https://mastodon.online/tags/nations" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>nations</span></a> while <a href="https://mastodon.online/tags/denigrating" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>denigrating</span></a> those from <a href="https://mastodon.online/tags/LatinAmerica" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LatinAmerica</span></a>, and primarily <a href="https://mastodon.online/tags/Black" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Black</span></a> majority <a href="https://mastodon.online/tags/Countries" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Countries</span></a> </p><p><a href="https://mastodon.online/tags/Women" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Women</span></a> <a href="https://mastodon.online/tags/Transgender" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Transgender</span></a> <a href="https://mastodon.online/tags/LGBTQ" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LGBTQ</span></a> <a href="https://mastodon.online/tags/LGBTQIA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LGBTQIA</span></a> <a href="https://mastodon.online/tags/Conservatives" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Conservatives</span></a> <a href="https://mastodon.online/tags/Extremism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Extremism</span></a> <a href="https://mastodon.online/tags/Fascism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Fascism</span></a> <a href="https://mastodon.online/tags/RepublicanParty" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>RepublicanParty</span></a> <a href="https://mastodon.online/tags/Hate" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Hate</span></a> <a href="https://mastodon.online/tags/Bigotry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Bigotry</span></a> <a href="https://mastodon.online/tags/Discrimination" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Discrimination</span></a> <a href="https://mastodon.online/tags/WhiteSupremacy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>WhiteSupremacy</span></a> <a href="https://mastodon.online/tags/Racism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Racism</span></a> <a href="https://mastodon.online/tags/ThePartyOfHate" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ThePartyOfHate</span></a> <a href="https://mastodon.online/tags/BlackMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>BlackMastodon</span></a> </p><p><a href="https://amsterdamnews.com/news/2024/04/08/trump-doubles-down-on-racist-remarks-advocates-for-white-immigration-only/" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">amsterdamnews.com/news/2024/04</span><span class="invisible">/08/trump-doubles-down-on-racist-remarks-advocates-for-white-immigration-only/</span></a></p>
Scientific Frontline<p>Most current <a href="https://mastodon.social/tags/asthma" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>asthma</span></a> treatments stem from the idea that it is an <a href="https://mastodon.social/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> disease. Yet, the life-threatening feature of asthma is the attack or the constriction of airways, making breathing difficult.<br><a href="https://mastodon.social/tags/Biomedical" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Biomedical</span></a> <a href="https://mastodon.social/tags/Medical" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Medical</span></a> <a href="https://mastodon.social/tags/sflorg" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>sflorg</span></a><br><a href="https://www.sflorg.com/2024/04/bmed04052401.html" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">sflorg.com/2024/04/bmed0405240</span><span class="invisible">1.html</span></a></p>
Susan Larson ♀️🏳️‍🌈🏳️‍⚧️🌈<p>The <a href="https://mastodon.online/tags/GOP" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>GOP</span></a> <a href="https://mastodon.online/tags/Flamethrower" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Flamethrower</span></a> With a <a href="https://mastodon.online/tags/Extremist" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Extremist</span></a> <a href="https://mastodon.online/tags/RightWing" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>RightWing</span></a> Vision for <a href="https://mastodon.online/tags/NorthCarolina" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>NorthCarolina</span></a></p><p><a href="https://mastodon.online/tags/MarkRobinson" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MarkRobinson</span></a>, <a href="https://mastodon.online/tags/Republican" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Republican</span></a> <a href="https://mastodon.online/tags/nominee" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>nominee</span></a> for <a href="https://mastodon.online/tags/governor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>governor</span></a>, history of <a href="https://mastodon.online/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> <a href="https://mastodon.online/tags/statements" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>statements</span></a> including calling for weaving <a href="https://mastodon.online/tags/conservative" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>conservative</span></a> <a href="https://mastodon.online/tags/religious" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>religious</span></a> <a href="https://mastodon.online/tags/beliefs" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>beliefs</span></a> into the <a href="https://mastodon.online/tags/fabric" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>fabric</span></a> of <a href="https://mastodon.online/tags/government" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>government</span></a>. </p><p><a href="https://mastodon.online/tags/Women" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Women</span></a> <a href="https://mastodon.online/tags/Transgender" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Transgender</span></a> <a href="https://mastodon.online/tags/LGBTQ" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LGBTQ</span></a> <a href="https://mastodon.online/tags/LGBTQIA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LGBTQIA</span></a> <a href="https://mastodon.online/tags/NorthCarolina" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>NorthCarolina</span></a> <a href="https://mastodon.online/tags/Conservatives" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Conservatives</span></a> <a href="https://mastodon.online/tags/Extremism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Extremism</span></a> <a href="https://mastodon.online/tags/Fascism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Fascism</span></a> <a href="https://mastodon.online/tags/Religion" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Religion</span></a> <a href="https://mastodon.online/tags/RepublicanParty" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>RepublicanParty</span></a> <a href="https://mastodon.online/tags/Hate" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Hate</span></a> <a href="https://mastodon.online/tags/Bigotry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Bigotry</span></a> <a href="https://mastodon.online/tags/Violence" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Violence</span></a> <a href="https://mastodon.online/tags/Genocide" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Genocide</span></a> <a href="https://mastodon.online/tags/Discrimination" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Discrimination</span></a> <a href="https://mastodon.online/tags/Transphobia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Transphobia</span></a> <a href="https://mastodon.online/tags/ThePartyOfHate" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ThePartyOfHate</span></a> <a href="https://mastodon.online/tags/EmptyThePews" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>EmptyThePews</span></a> </p><p><a href="https://www.nytimes.com/2024/03/18/us/politics/mark-robinson-north-carolina.html" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nytimes.com/2024/03/18/us/poli</span><span class="invisible">tics/mark-robinson-north-carolina.html</span></a></p>
Steve Dustcircle 🌹<p><a href="https://masto.ai/tags/Smoking" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Smoking</span></a> Has Long-Term Effects on Your <a href="https://masto.ai/tags/ImmuneSystem" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ImmuneSystem</span></a>, New Study Finds</p><p><a href="https://www.inverse.com/health/smoking-alter-immune-system-forever" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">inverse.com/health/smoking-alt</span><span class="invisible">er-immune-system-forever</span></a></p><p>Smoking shapes your adaptive <a href="https://masto.ai/tags/immune" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immune</span></a> system into something more over-reactive and pro-<a href="https://masto.ai/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> even long after you quit.</p>
DoomsdaysCW<p><a href="https://kolektiva.social/tags/Cannabinoids" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Cannabinoids</span></a> as novel <a href="https://kolektiva.social/tags/AntiInflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>AntiInflammatory</span></a> drugs</p><p>by Prakash Nagarkatti, et al.<br>October, 2009</p><p>Abstract:</p><p>"Cannabinoids are a group of compounds that mediate their effects through cannabinoid receptors. The discovery of Δ9-tetrahydrocannabinol (<a href="https://kolektiva.social/tags/THC" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>THC</span></a>) as the major psychoactive principle in marijuana, as well as the identification of <a href="https://kolektiva.social/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabinoid</span></a> receptors and their endogenous ligands, has led to a significant growth in research aimed at understanding the physiological functions of cannabinoids. Cannabinoid receptors include CB1, which is predominantly expressed in the brain, and CB2, which is primarily found on the cells of the immune system. The fact that both CB1 and CB2 receptors have been found on <a href="https://kolektiva.social/tags/immune" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immune</span></a> cells suggests that cannabinoids play an important role in the regulation of the immune system. Recent studies demonstrated that administration of THC into mice triggered marked apoptosis in T cells and dendritic cells, resulting in immunosuppression. In addition, several studies showed that cannabinoids downregulate <a href="https://kolektiva.social/tags/cytokine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cytokine</span></a> and chemokine production and, in some models, upregulate T-regulatory cells (Tregs) as a mechanism to suppress <a href="https://kolektiva.social/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> responses. The <a href="https://kolektiva.social/tags/endocannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>endocannabinoid</span></a> system is also involved in <a href="https://kolektiva.social/tags/immunoregulation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immunoregulation</span></a>. For example, administration of endocannabinoids or use of inhibitors of enzymes that break down the endocannabinoids, led to immunosuppression and recovery from immune-mediated injury to organs such as the liver. Manipulation of endocannabinoids and/or use of exogenous cannabinoids in vivo can constitute a potent treatment modality against inflammatory disorders. This review will focus on the potential use of cannabinoids as a new class of anti-inflammatory agents against a number of inflammatory and autoimmune diseases that are primarily triggered by activated T cells or other cellular immune components."</p><p>Executive summary</p><p>- Cannabinoids, the active components of <a href="https://kolektiva.social/tags/CannabisSativa" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CannabisSativa</span></a>, and endogenous cannabinoids mediate their effects through activation of specific cannabinoid receptors known as cannabinoid receptor 1 and 2 (CB1 and CB2).</p><p>- The cannabinoid system has been shown both in vivo and in vitro to be involved in regulating the immune system through its immunomodulatory properties.</p><p>- Cannabinoids suppress inflammatory response and subsequently attenuate disease symptoms. This property of cannabinoids is mediated through multiple pathways such as induction of apoptosis in activated immune cells, suppression of cytokines and chemokines at inflammatory sites and upregulation of FoxP3+ regulatory T cells.</p><p>- Cannabinoids have been tested in several experimental models of autoimmune disorders such as <a href="https://kolektiva.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MultipleSclerosis</span></a>, <a href="https://kolektiva.social/tags/RheumatoidArthritis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>RheumatoidArthritis</span></a>, <a href="https://kolektiva.social/tags/colitis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>colitis</span></a> and <a href="https://kolektiva.social/tags/hepatitis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>hepatitis</span></a> and have been shown to protect the host from the pathogenesis through induction of multiple anti-inflammatory pathways.</p><p>- Cannabinoids may also be beneficial in certain types of <a href="https://kolektiva.social/tags/cancers" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cancers</span></a> that are triggered by <a href="https://kolektiva.social/tags/ChronicInflammation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ChronicInflammation</span></a> In such instances, cannabinoids can either directly inhibit tumor growth or suppress inflammation and tumor angiogenesis.</p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">ncbi.nlm.nih.gov/pmc/articles/</span><span class="invisible">PMC2828614/</span></a></p>
DoomsdaysCW<p><a href="https://kolektiva.social/tags/Cannabidiol" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Cannabidiol</span></a> (<a href="https://kolektiva.social/tags/CBD" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CBD</span></a>): a killer for <a href="https://kolektiva.social/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> rheumatoid <a href="https://kolektiva.social/tags/arthritis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>arthritis</span></a> synovial fibroblasts</p><p>Published: 01 September 2020<br>by Torsten Lowin, et al.</p><p>Abstract:</p><p>"Cannabidiol (CBD) is a non-intoxicating phytocannabinoid from cannabis sativa that has demonstrated anti-inflammatory effects in several inflammatory conditions including arthritis. However, CBD binds to several receptors and enzymes and, therefore, its mode of action remains elusive. In this study, we show that CBD increases intracellular calcium levels, reduces cell viability and IL-6/IL-8/MMP-3 production of rheumatoid arthritis synovial fibroblasts (RASF). These effects were pronounced under inflammatory conditions by activating transient receptor potential ankyrin (TRPA1), and by opening of the mitochondrial permeability transition pore. Changes in intracellular calcium and cell viability were determined by using the fluorescent dyes Cal-520/PoPo3 together with cell titer blue and the luminescent dye RealTime-glo. Cell-based impedance measurements were conducted with the XCELLigence system and TRPA1 protein was detected by flow cytometry. Cytokine production was evaluated by ELISA. CBD reduced cell viability, proliferation, and IL-6/IL-8 production of RASF. Moreover, CBD increased intracellular calcium and uptake of the cationic viability dye PoPo3 in RASF, which was enhanced by pre-treatment with TNF. Concomitant incubation of CBD with the TRPA1 antagonist A967079 but not the TRPV1 antagonist capsazepine reduced the effects of CBD on calcium and PoPo3 uptake. In addition, an inhibitor of the mitochondrial permeability transition pore, cyclosporin A, also blocked the effects of CBD on cell viability and IL-8 production. PoPo3 uptake was inhibited by the voltage-dependent anion-selective channel inhibitor DIDS and Decynium-22, an inhibitor for all organic cation transporter isoforms. CBD increases intracellular calcium levels, reduces cell viability, and IL-6/IL-8/MMP-3 production of RASF by activating TRPA1 and mitochondrial targets. This effect was enhanced by pre-treatment with TNF suggesting that CBD preferentially targets activated, pro-inflammatory RASF. Thus, CBD possesses anti-arthritic activity and might ameliorate arthritis via targeting synovial fibroblasts under inflammatory conditions."</p><p>Source:<br><a href="https://www.nature.com/articles/s41419-020-02892-1" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s41419-020</span><span class="invisible">-02892-1</span></a> </p><p><a href="https://kolektiva.social/tags/Cannabis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Cannabis</span></a> <a href="https://kolektiva.social/tags/AntiInflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>AntiInflammatory</span></a></p>
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