Daniel Dvorkin<p>I have in fact read the <a href="https://qoto.org/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a> (<a href="https://qoto.org/tags/medication" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>medication</span></a> <a href="https://qoto.org/tags/information" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>information</span></a> sheet) for the <a href="https://qoto.org/tags/Pfizer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Pfizer</span></a> <a href="https://qoto.org/tags/vaccine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>vaccine</span></a>, since that's the one I've been getting, and I do the same for every prescribed <a href="https://qoto.org/tags/medication" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>medication</span></a> I take. People act like it's some kind of super-secret information, when really it's as easily accessible as a Mike <a href="https://qoto.org/tags/Waltz" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Waltz</span></a> chat on <a href="https://qoto.org/tags/Signal" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Signal</span></a>.</p>
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#MIS
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Tino Eberl<p><a href="https://mastodon.online/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a>-C, eine seltene, aber schwere Entzündung nach <a href="https://mastodon.online/tags/COVID19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID19</span></a> bei Kindern, wird durch die Reaktivierung des <a href="https://mastodon.online/tags/EpsteinBarr" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>EpsteinBarr</span></a>-Virus ausgelöst.</p><p>Das <a href="https://mastodon.online/tags/Virus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Virus</span></a>, das meist unbemerkt im Körper bleibt, kann durch eine gestörte <a href="https://mastodon.online/tags/Immunabwehr" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Immunabwehr</span></a> erneut aktiv werden. </p><p>Forschende der <a href="https://mastodon.online/tags/Charit%C3%A9" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Charité</span></a> haben entdeckt, dass der Botenstoff <a href="https://mastodon.online/tags/TGF%CE%B2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>TGFβ</span></a> diesen Prozess verstärkt. Eine gezielte Hemmung könnte Behandlungswege für MIS-C und möglicherweise auch für <a href="https://mastodon.online/tags/LongCovid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LongCovid</span></a> eröffnen.</p><p><a href="https://www.charite.de/en/service/press_reports/artikel/detail/cause_of_post_covid_inflammatory_shock_in_children_identified" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">charite.de/en/service/press_re</span><span class="invisible">ports/artikel/detail/cause_of_post_covid_inflammatory_shock_in_children_identified</span></a></p><p><a href="https://mastodon.online/tags/Medizin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Medizin</span></a> <a href="https://mastodon.online/tags/Science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Science</span></a> <a href="https://mastodon.online/tags/Virologie" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Virologie</span></a></p>
emeritrix<p>Those against Diversity Equity and Inclusion are presumably in favor of Monotony, Injustice, and Segregation. </p><p>anti <a href="https://kolektiva.social/tags/DEI" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>DEI</span></a> = pro <a href="https://kolektiva.social/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a></p>
1. Neu-Kelte 🌻💙💛🌻<p><a href="https://hear-me.social/tags/LegendaryWednesday" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LegendaryWednesday</span></a>: `When <a href="https://hear-me.social/tags/Mis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Mis</span></a> found the decapitated corpse of her beloved father her grief overwhelmed her, and she flung herself across his body and licked and sucked at his bloody wounds to try to heal them, just as an animal might.<br>But nothing could restore him to life, and when finally she understood this Mis staggered to her feet and wailed and clawed at her ravaged, wet face and her blood-stained clothing. Finally, in the utter, unstoppable agony of her despair, she cracked. Taken by the extremity of her madness, she rose up into the air like a bird and with a long high-pitched howl which shook those who heard it to the very core, she flew away into the heart of the Sliabh Mis mountains.` <a href="https://hear-me.social/tags/Celtic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Celtic</span></a><br>Source: Sharon Blackie „If Women Rose Rooted“<br><a href="https://x.com/NeuKelte/status/1727360755257720983?t=XiUlmz9z4jyqzHxdumwTNA&s=09" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">x.com/NeuKelte/status/17273607</span><span class="invisible">55257720983?t=XiUlmz9z4jyqzHxdumwTNA&s=09</span></a></p>
Solarbird :flag_cascadia:<p>How? With MORSE?!</p><p><a href="https://mastodon.murkworks.net/tags/IT" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>IT</span></a> <a href="https://mastodon.murkworks.net/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a> <a href="https://mastodon.murkworks.net/tags/wtaf" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>wtaf</span></a> <a href="https://mastodon.murkworks.net/tags/wtf" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>wtf</span></a> <a href="https://mastodon.murkworks.net/tags/bothell" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>bothell</span></a> <a href="https://mastodon.murkworks.net/tags/seattle" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>seattle</span></a> <a href="https://mastodon.murkworks.net/tags/SoundOn" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SoundOn</span></a></p>
RS, Author, Novelist, Prosaist<p><a href="https://eldritch.cafe/tags/WritersCoffeeClub" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>WritersCoffeeClub</span></a> Ch 12 Nbr 15 FEV— Have you used any form of AI to help in creating your work? Do you have a red line? Where is it? <strong>Full Essay Version</strong></p><p>I've been around long enough that I remember when the <a href="https://eldritch.cafe/tags/Altair" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Altair</span></a> 8080 (the first commercial personal computer) got a full page ad in Scientific American. My BFF and I talked about it after school (11th grade, I think?) for hours. I had my own slimline phone on my own extension. I was a privileged kid. The <a href="https://eldritch.cafe/tags/computer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>computer</span></a> club had a teletype connection to a computer that ran <a href="https://eldritch.cafe/tags/BASIC" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>BASIC</span></a>. We also had access to an <a href="https://eldritch.cafe/tags/IBM" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>IBM</span></a> mainframe assembler using <a href="https://eldritch.cafe/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a> (pencil in) punch cards. A friend built an <a href="https://eldritch.cafe/tags/IMSAI" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>IMSAI</span></a> 8080 with 256 bytes of memory and it played songs we could listen to by tuning to part of the FM band influenced by the frequency of bits passing through the memory buss. </p><p>Why do I bring this up? The first things we programmed (after ping-pong on the toggle switch lights, Star Trek, and later adventure games) where types of artificial intelligence. We've been "teaching" computers to "think" for us since we could rip them away from the greedy money grubbers who wanted to do things like <em>accounting</em> and <em>payroll</em>. Current concepts of AI rely on pattern matching against databases, in very simplified terms. Early <a href="https://eldritch.cafe/tags/AI" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>AI</span></a> were procedural, and if it solved your math problem, spelled your word correctly, or found data in the noise, it <em>was</em> intelligent. It is inescapable that unless we write longhand or type on a typewriter, that we have used what someone terms AI.</p><p>Anybody remember Clippy? </p><p>The key to this question, and how I am going to take it, is to focus on the word "creating." To me, that highlights <em>generating</em> something. Text. Graphics. Though this implies <a href="https://eldritch.cafe/tags/genAI" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>genAI</span></a> (the current thing, something like <a href="https://eldritch.cafe/tags/Diffusion" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Diffusion</span></a> or <a href="https://eldritch.cafe/tags/ChatGPT" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ChatGPT</span></a>). It also means graphic tools that I use to remove and add image elements to photos, or otherwise intelligently improve them in ways I could <em>imagine</em> but was previously incapable due to lack of talent, practice, or understanding of the unenhanced tools. </p><p>As for text, I remember once writing a chatbot psychologist. IF-THEN-ELSE. In BASIC, back in high school or it may have been in an equivalent language on a DEC-10 at university. It did not pass the Turing Test, but it could lift one's mood, which could help with me "creating" work!</p><p>I've no interest in using something like chatGPT to build a story from prompts. It would be the program's story, not mine. It would be a Cliff Notes version of an unwritten story, <em>summarized,</em> never provided a soul, before even being written. Because these things work by pattern matching and predicting what would be the next word (based on an average of everybody's writing or specific genres or authors), it would be pure statistical fabrication—not even fabulation, which implies creative fantasy. It would be a story with none of the emotion, feeling, or meaning I'd put into it. It would be phantom chatter masquerading as wit through statistical randomness. No enlightenment possible, except by accident.</p><p>As an author, why would I even try to replace myself, or create the tools for others to try to do the same? I suspect people that do, do so as I wrote above because they are "incapable due to lack of talent, practice, or understanding of the tools." I'll add, also laziness, though I tar myself with the same brush as I wrote above. </p><p>Never discount greed. Authors cost money. Computers cost once.</p><p>In any case, the AI tools built into the software I do use barely save me time as it is. I can't start a dictation with the 1st person personal pronoun on any of my systems. Statistically, more people start dictation with "Hi" then "I," so I <em>always</em> have to correct that. Thanks to auto-incorrect, even the words I spell correctly (few enough as it is) get changed. In this very article, the tool insisted I had a "teletype connection to a <em>commuter!</em>" Not only do I have to be aware of my own tendency toward grammar issues and typos, I have to proof for AI typos, including chaining typos since the tools keep track of some meaning and can spawn a hellacious brew of misconception and embarrassment should it slip out to readers. I know what I mean to write. Sometimes I find myself overruled by my own tools.</p><p><strong>Have I used AI?</strong> Not genAI. Procedural tools, yes. Not for willingly generating text.</p><p><strong>Red line?</strong> Yes. No generating story or text. What's the point? </p><p>[Author retains copyright (c)2024 R.S.]</p><p><a href="https://eldritch.cafe/tags/BoostingIsSharing" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>BoostingIsSharing</span></a> and <a href="https://eldritch.cafe/tags/CommentingIsCool" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CommentingIsCool</span></a></p><p><a href="https://eldritch.cafe/tags/fiction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>fiction</span></a> <a href="https://eldritch.cafe/tags/romance" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>romance</span></a> <a href="https://eldritch.cafe/tags/fantasy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>fantasy</span></a> <a href="https://eldritch.cafe/tags/sf" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>sf</span></a> <a href="https://eldritch.cafe/tags/sff" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>sff</span></a> <a href="https://eldritch.cafe/tags/sciencefiction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>sciencefiction</span></a> <a href="https://eldritch.cafe/tags/writing" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>writing</span></a> <a href="https://eldritch.cafe/tags/writer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>writer</span></a> <a href="https://eldritch.cafe/tags/writers" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>writers</span></a> <a href="https://eldritch.cafe/tags/author" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>author</span></a> <a href="https://eldritch.cafe/tags/writingcommunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>writingcommunity</span></a> <a href="https://eldritch.cafe/tags/writersOfMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>writersOfMastodon</span></a> <br><a href="https://eldritch.cafe/tags/RSdiscussion" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>RSdiscussion</span></a> <a href="https://eldritch.cafe/tags/theComingLaborApocalypse" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>theComingLaborApocalypse</span></a></p>
Tom Kindlon<p>2/</p><p>"We identified previously undescribed relationships between spike IgG glycan modifications and inflammatory cytokines/chemokines that expand our understanding of IgG glycosylation changes that may impact COVID and MIS-C immunopathology."</p><p><a href="https://disabled.social/tags/Covid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Covid</span></a> <a href="https://disabled.social/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a>-C <a href="https://disabled.social/tags/MIS_C" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS_C</span></a> <br><a href="https://disabled.social/tags/CovidBrain" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CovidBrain</span></a><br><span class="h-card" translate="no"><a href="https://a.gup.pe/u/covid19" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>covid19</span></a></span> <a href="https://disabled.social/tags/COVID%E3%83%BC19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVIDー19</span></a> <a href="https://disabled.social/tags/COVID19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID19</span></a> <a href="https://disabled.social/tags/COVID" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID</span></a> <a href="https://disabled.social/tags/COVID_19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID_19</span></a> <a href="https://disabled.social/tags/SARSCoV2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SARSCoV2</span></a> <span class="h-card" translate="no"><a href="https://chirp.social/@novid" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>novid@chirp.social</span></a></span> <a href="https://disabled.social/tags/novid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>novid</span></a> <span class="h-card" translate="no"><a href="https://a.gup.pe/u/novid" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>novid@a.gup.pe</span></a></span> <a href="https://disabled.social/tags/CovidIsNotOver" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CovidIsNotOver</span></a> <a href="https://disabled.social/tags/auscovid19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>auscovid19</span></a> <span class="h-card" translate="no"><a href="https://a.gup.pe/u/auscovid19" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>auscovid19</span></a></span></p>
1. Neu-Kelte 💙💛🌻<p>`Daughter of a warrior, <a href="https://todon.eu/tags/Mis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Mis</span></a> found her father’s bloodied body after a battle and, desperate with sorrow, drank his blood, which drove her mad. Mis went into the mountains and lived by killing animals with her bare hands, until she heard a harper named Dubh Rois singing. His love redeemed her and the towering mountain range in which she had walked during her mental derangement were named after her Slieve Mish.`<br>Source: Patricia Monaghan `Encyclopedia of <a href="https://todon.eu/tags/Celtic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Celtic</span></a> <a href="https://todon.eu/tags/Mythology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Mythology</span></a> and Folklore`</p>
TomAoki<p><span class="h-card" translate="no"><a href="https://mstdn.party/@argv_minus_one" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>argv_minus_one</span></a></span> <span class="h-card" translate="no"><a href="https://mastodon.bsd.cafe/@stefano" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>stefano</span></a></span> </p><p>Unfortunately, computers needs to be much, much and much more faster and intelligent for we, Japanese.<br>Conversion from ASCII-expressed string to Kanji/Kana strings by IME (until early 90's they were called FEP [Front End Processor], as they works between keyboard and application inputs) are still far from perfect (singificantly improved, though) and interrupts thinking, thus, ideas often disappears.<br>Some IMEs introduced clowd servers to attempt conversions more precise, but currently it made the conversion slower.<br>Maybe we need LLM and mighty AI on local side purely for IME.</p><p><a href="https://mastodon.bsd.cafe/tags/IME" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>IME</span></a> <a href="https://mastodon.bsd.cafe/tags/FEP" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>FEP</span></a> <a href="https://mastodon.bsd.cafe/tags/ja_JP" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ja_JP</span></a> <a href="https://mastodon.bsd.cafe/tags/mis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>mis</span></a>-conversion <a href="https://mastodon.bsd.cafe/tags/slow" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>slow</span></a> <a href="https://mastodon.bsd.cafe/tags/LLM" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LLM</span></a></p>
Tom Kindlon<p>The Spectrum of Postacute Sequelae of <a href="https://disabled.social/tags/COVID19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID19</span></a> in Children: From MIS-C to Long <a href="https://disabled.social/tags/COVID" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID</span></a></p><p><a href="https://www.annualreviews.org/content/journals/10.1146/annurev-virology-093022-011839" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">annualreviews.org/content/jour</span><span class="invisible">nals/10.1146/annurev-virology-093022-011839</span></a></p><p>"Shared pathophysiologic mechanisms suggest <a href="https://disabled.social/tags/longcovid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>longcovid</span></a> is a more indolent version of <a href="https://disabled.social/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a>-C"</p><p><a href="https://disabled.social/tags/LCKids" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LCKids</span></a></p><p><span class="h-card" translate="no"><a href="https://a.gup.pe/u/longcovid" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>longcovid</span></a></span><br><a href="https://disabled.social/tags/LongCovid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LongCovid</span></a> <a href="https://disabled.social/tags/PwLC" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PwLC</span></a> <a href="https://disabled.social/tags/PostCovidSyndrome" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PostCovidSyndrome</span></a> <a href="https://disabled.social/tags/LC" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LC</span></a> <a href="https://disabled.social/tags/PASC" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PASC</span></a> <a href="https://disabled.social/tags/postcovid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>postcovid</span></a> <br><a href="https://disabled.social/tags/CovidBrain" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CovidBrain</span></a><br><span class="h-card" translate="no"><a href="https://a.gup.pe/u/covid19" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>covid19</span></a></span> <a href="https://disabled.social/tags/COVID%E3%83%BC19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVIDー19</span></a> <a href="https://disabled.social/tags/COVID" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID</span></a> <a href="https://disabled.social/tags/COVID_19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID_19</span></a> <a href="https://disabled.social/tags/SARSCoV2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SARSCoV2</span></a> <span class="h-card" translate="no"><a href="https://chirp.social/@novid" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>novid</span></a></span> <a href="https://disabled.social/tags/novid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>novid</span></a> <a href="https://disabled.social/tags/CovidIsNotOver" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CovidIsNotOver</span></a> <a href="https://disabled.social/tags/auscovid19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>auscovid19</span></a> <span class="h-card" translate="no"><a href="https://a.gup.pe/u/auscovid19" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>auscovid19</span></a></span></p>
Giuseppe Michieli<p>''... a recent increase in cases of multisystem inflammatory syndrome in <a href="https://mstdn.science/tags/children" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>children</span></a> (<a href="https://mstdn.science/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a>-C) following <a href="https://mstdn.science/tags/SARS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SARS</span></a>-CoV-2 <a href="https://mstdn.science/tags/infection" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>infection</span></a> in the <a href="https://mstdn.science/tags/US" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>US</span></a> has been reported - Healthcare providers should administer influenza, COVID-19, and RSV immunizations now to patients, if recommended. ''</p>
MittenGirlPeach 🐅 ⚾️<p>And . . . Nature wins. The race at MIS will resume tomorrow at noon. It’s been a soggy Sunday in the Irish Hills! <a href="https://mastodon.social/tags/NASCAR" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>NASCAR</span></a> <a href="https://mastodon.social/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a> <a href="https://mastodon.social/tags/PureMichigan" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PureMichigan</span></a></p>
MittenGirlPeach 🐅 ⚾️<p>Looks like storms/rain may disrupt the nascar race tomorrow in my hometown. And the rain will linger! Monday looks like a good day for the garden. <a href="https://www.mlive.com/weather/2023/08/a-few-changes-to-early-week-storm-you-should-know.html" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">mlive.com/weather/2023/08/a-fe</span><span class="invisible">w-changes-to-early-week-storm-you-should-know.html</span></a> <a href="https://mastodon.social/tags/PureMichigan" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PureMichigan</span></a> <a href="https://mastodon.social/tags/NASCAR" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>NASCAR</span></a> <a href="https://mastodon.social/tags/FireKeepers400" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>FireKeepers400</span></a> <a href="https://mastodon.social/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a> <a href="https://mastodon.social/tags/Storms" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Storms</span></a> <a href="https://mastodon.social/tags/miwx" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>miwx</span></a></p>
Rückruf-Portal<p><a href="https://mastodon.social/tags/R%C3%9CCKRUF" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>RÜCKRUF</span></a> | <a href="https://mastodon.social/tags/WARNUNG" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>WARNUNG</span></a> | LEBENSMITTELWARNUNG: <a href="https://mastodon.social/tags/SALMONELLEN" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SALMONELLEN</span></a> sind auch in <a href="https://mastodon.social/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a> 'Tahin <a href="https://mastodon.social/tags/Sesammus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Sesammus</span></a>' nicht auszuschließen > Bei schweren / anhaltenden Symptomen ist UNBEDINGT ärztliche Hilfe aufzusuchen</p><p>Quelle:<br><a href="https://www.lebensmittelwarnung.de/bvl-lmw-de/detail/lebensmittel/90793" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">lebensmittelwarnung.de/bvl-lmw</span><span class="invisible">-de/detail/lebensmittel/90793</span></a></p><p>Weitere aktuelle Meldungen:<br><a href="https://www.produktrueckrufe.de/" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="">produktrueckrufe.de/</span><span class="invisible"></span></a></p>
Anita Y Cheng<p><a href="https://mastodon.publicinterest.town/tags/COVID" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID</span></a> updates! XBB.1.5 in NYC seems to be the same severity as the other omicron <a href="https://mastodon.publicinterest.town/tags/variants" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>variants</span></a>. (No cool “kraken” name for it, oh well.)</p><p>They tested treating <a href="https://mastodon.publicinterest.town/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a>-C in children with immunoglobulin or glucocorticoids (or both) and there was no differences between them, which ultimately means more treatment options.</p><p>There was a summary of cases involving fatal brain swelling from <a href="https://mastodon.publicinterest.town/tags/omicron" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>omicron</span></a> COVID in (unvaccinated) kids in Taiwan.😞 7/</p><p> <a href="https://mastodon.publicinterest.town/tags/TWiVTLDR" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>TWiVTLDR</span></a></p>
Hannah Strobel<p><span class="h-card"><a href="https://mastodon.green/@fitterhappierAJ" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>fitterhappierAJ</span></a></span> <span class="h-card"><a href="https://a.gup.pe/u/whn" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>whn</span></a></span> </p><p>RT @casanova_lab</p><p>13/ This mechanism of disease may operate generally, facilitating the search for other genetic lesions in children with <a href="https://critcare.social/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a>-C</p><p>14/ This observation also suggests that other forms of <a href="https://critcare.social/tags/Kawasaki" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Kawasaki</span></a> Disease may be deciphered by searching for <a href="https://critcare.social/tags/monogenic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>monogenic</span></a> lesions in cohorts of patients whose Kawasaki was <a href="https://critcare.social/tags/triggered" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>triggered</span></a> by one <a href="https://critcare.social/tags/virus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>virus</span></a> or a group of related viruses</p>
Hannah Strobel<p><span class="h-card"><a href="https://mastodon.green/@fitterhappierAJ" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>fitterhappierAJ</span></a></span> <span class="h-card"><a href="https://a.gup.pe/u/whn" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>whn</span></a></span> </p><p>RT @casanova_lab</p><p>12/ Interestingly, while <a href="https://critcare.social/tags/inborn" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inborn</span></a> errors or auto-Abs that impair type I <a href="https://critcare.social/tags/IFN" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>IFN</span></a> activity underlie critical <a href="https://critcare.social/tags/COVID" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID</span></a>-19 €pneumonia (science.org/doi/10.1126/sc…, science.org/doi/10.1126/sc…), the deficiency of this single type I IFN-inducible <a href="https://critcare.social/tags/pathway" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>pathway</span></a> does not – on the contrary, it underlies <a href="https://critcare.social/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a>-C</p><p><a href="https://www.science.org/doi/10.1126/science.abd4570" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">science.org/doi/10.1126/scienc</span><span class="invisible">e.abd4570</span></a></p>
Audrey Odom John MD PhD<p>First hint that there might be genetic defects in children with <a href="https://med-mastodon.com/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a>-C: "We report autosomal recessive deficiencies of OAS1, OAS2, or RNASEL in five unrelated children with MIS-C. "</p><p>Cool work from Jean-Laurent Cassanova and many team members:</p><p><a href="https://www.science.org/doi/10.1126/science.abo3627" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">science.org/doi/10.1126/scienc</span><span class="invisible">e.abo3627</span></a></p><p><a href="https://med-mastodon.com/tags/IDMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>IDMastodon</span></a> <a href="https://med-mastodon.com/tags/PedsIDMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PedsIDMastodon</span></a> <a href="https://med-mastodon.com/tags/PedsID" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PedsID</span></a> <a href="https://med-mastodon.com/tags/SARSCov2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SARSCov2</span></a></p>
Hannah Strobel<p><span class="h-card"><a href="https://mastodon.green/@fitterhappierAJ" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>fitterhappierAJ</span></a></span> <span class="h-card"><a href="https://a.gup.pe/u/whn" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>whn</span></a></span> </p><p>🧵💥 RT @casanova_lab</p><p>11/ Overall, <a href="https://critcare.social/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a>-C can be caused by autosomal recessive defects of the OAS-RNase L <a href="https://critcare.social/tags/pathway" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>pathway</span></a>, which unleash the activation of mononuclear phagocytes by <a href="https://critcare.social/tags/SARS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SARS</span></a>-CoV-2-triggered dsRNA, thereby possibly facilitating the expansion of Vbeta21.3 T <a href="https://critcare.social/tags/cells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cells</span></a></p>
Hannah Strobel<p><span class="h-card"><a href="https://mastodon.green/@fitterhappierAJ" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>fitterhappierAJ</span></a></span> </p><p>RT @casanova_lab</p><p>4/ We previously proposed that <a href="https://critcare.social/tags/MIS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MIS</span></a>-C is a type of <a href="https://critcare.social/tags/Kawasaki" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Kawasaki</span></a> <a href="https://critcare.social/tags/Disease" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Disease</span></a> <a href="https://critcare.social/tags/triggered" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>triggered</span></a> by a single <a href="https://critcare.social/tags/virus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>virus</span></a> and might be caused by monogenic inborn errors of <a href="https://critcare.social/tags/immunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immunity</span></a> that can be detected by searching for <a href="https://critcare.social/tags/genetic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>genetic</span></a> homogeneity in a sufficiently large <a href="https://critcare.social/tags/cohort" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cohort</span></a> of <a href="https://critcare.social/tags/patients" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>patients</span></a> (doi.org/10.1084/jem.20…)</p><p><a href="https://rupress.org/jem/article/218/6/e20210446/212029/SARS-CoV-2-related-MIS-C-A-key-to-the-viral-and" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="ellipsis">rupress.org/jem/article/218/6/</span><span class="invisible">e20210446/212029/SARS-CoV-2-related-MIS-C-A-key-to-the-viral-and</span></a></p><p><a href="https://critcare.social/tags/sarscov2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>sarscov2</span></a><br><span class="h-card"><a href="https://a.gup.pe/u/whn" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>whn</span></a></span></p>
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