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#Superbug

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michael

2-Apr-2025
New #antibiotic for multidrug resistant #superbug
Researchers from the universities in Konstanz and Vienna discover a new class of antibiotic that selectively targets Neisseria gonorrhoeae, the bacterium that causes #gonorrhoea.

eurekalert.org/news-releases/1 #science #medicine #AntibioticsResistance

EurekAlert!New antibiotic for multidrug resistant superbugResearchers from the universities in Konstanz and Vienna discover a new class of antibiotic that selectively targets Neisseria gonorrhoeae, the bacterium that causes gonorrhoea. These substances trigger a self-destruction program, which also operates in multi-resistant variants of the pathogen. The novel findings are published in the current issue of Nature Microbiology.
Benjamin Carr, Ph.D. 👨🏻‍💻🧬

#AI cracks #superbug problem in two days that took scientists years
Their hypothesis is that the superbugs can form a tail from different #viruses which allows them to spread between species. Prof Penades likened it to the superbugs having "keys" which enabled them to move from home to home, or host species to host species.
Critically, this hypothesis was unique to the research team and had not been published anywhere else. Nobody in the team had shared their findings.
bbc.com/news/articles/clyz6e9e

www.bbc.comAI cracks superbug problem in two days that took scientists yearsThe lead researcher has told the BBC he was so astounded he assumed his computer had been hacked.
Benjamin Carr, Ph.D. 👨🏻‍💻🧬

Experimental #antibiotic kills deadly #superbug, opens whole new class of #drugs
Relatively large molecule clogs a transport system, leading to lethal toxicity. In this case, the new #drug—dubbed #zosurabalpin—fights off the #GramNegative #bacterium carbapenem-resistant Acinetobacter baumannii, aka CRAB. Though it may sound obscure, it's an opportunistic, invasive #bacteria that often strikes hospitalized and critically ill patients, causing deadly #infections worldwide. arstechnica.com/science/2024/0

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