Tutorial paper illustrating how to develop planned contrasts (as an alternative to #PostHoc comparisons) in #Rstats, including empirical examples with reproducible data:
https://journals.sagepub.com/doi/full/10.1177/25152459241293110
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#studydesign
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Day 9Master #fNIRS Research with Proven #BestPractices 
Stay informed and enhance the quality of your studies by following these best practices for fNIRS research. From study design to data reporting, this guide provides valuable insights to help you publish impactful research. 
Ready to refine your approach? https://doi.org/10.1117/1.NPh.8.1.012101
https://pubmed.ncbi.nlm.nih.gov/38401800/ Recreational MDMA doses do not elicit hepatotoxicity in HepG2 spheroids under normo- and hyperthermia (de Oliveira, et al, 2024) #mdma #fda #psychedelic #psychedelics #psychedelicresearch #fda #studydesign #litreview #ptsd #psychedelicassistedtherapy #mdmaassistedtherapy #entactogens #neuroscience
https://pubmed.ncbi.nlm.nih.gov/38982828/ Entactogen Effects of Ketamine: A Reverse-Translational Study (Hess, et al, 2024) #ketamine #psychedelic #psychedelicresearch #entactogens #psychedelics #depression #neuroscience #fda #studydesign #mentalhealth #litreview #antidepressant #ketaminetherapy #psychedelictherapy
https://pubmed.ncbi.nlm.nih.gov/38979497/ Ketamine in the effective management of chronic pain, depression, and posttraumatic stress disorder for Veterans: A meta-analysis and systematic review (Liu, et al, 2024) #ketamine #pain #depression #ptsd #psychedelic #psychedelics #psychedelicresearch #psychedelicmentalhealth #mentalhealth #veterans #chronicpain #fda #studydesign #litreview #ketamineassistedtherapy #psychedelicassistedtherapy
https://psychedelicmentalhealth.net/neural-correlates-subjective-experiences-meditation-psychedelics-ketamine-psychotherapy/ Neural correlates and subjective experiences in meditation vs psychedelics, including ketamine (Preliminary Lit Review)
A preliminary, evolving review of the literature. (Ongoing Draft) | Psychedelic Institute of Mental Health & Family Therapy #meditation #psychedelics #ketamine #ayahausca #lsd #psilocybin #dmt #neuroscience #Psychedelic #Litreview #research #studydesign #fda #mdma #psychedelicassistedpsychotherapy #cognitivebehavioraltherapy
Psychedelic Institute of Mental Health & Family Therapy · Neural correlates and subjective experiences in meditation vs psychedelics, including ketamine (Preliminary Lit Review)A preliminary, evolving review of the literature. (Ongoing Draft) | Psychedelic Institute of Mental Health & Family Therapy
https://psychedelicmentalhealth.net/psychedelic-therapy-cognitive-behavioral-therapy-ketamine-context-competencies/ Psychedelic Cognitive Behavioral Therapy: On Ketamine, Context and Competencies in "Assisted-Psychotherapy” #psychedelic #psychedelics #cognitivebehavioraltherapy #psychedelicresearch #studydesign #fda #mdma #cbt #ketamine #ketamineassistedtherapy #psychedelicassistedtherapy #ketamineassistedpsychotherapy #psychedelicassistedpsychotherapy #lsd #psilocybin #neuroscience #telehealth
Psychedelic Institute of Mental Health & Family Therapy · Psychedelic Cognitive Behavioral Therapy: On Ketamine, Context and Competencies in "Assisted-Psychotherapy”There are many tools to help a psychotherapist help clients learn to speak the language of cognitive behavioral therapy, especially tools which may help facilitate therapeutic alliance, including, but not limited to telehealth.
Trying out ghost in anticipation of it joining the Fediverse. https://psychedelic-institute-of-mental-health.ghost.io/ #psychedelic #psychedelics #psychedelicassistedpsychotherapy #ketamineassistedpsychotherapy #cognitivebehavioraltherapy #studydesign #litreview #psychedelicresearch #psychedelictherapist #fediverse #ghostio
Psychedelic Institute of Mental HealthPsychedelic Institute of Mental HealthPsychedelic Therapy Research, News, Training | Palm Springs, Joshua Tree, Coachella Valley | https://psychedelictherapy.institute
https://psychedelictherapypalmsprings.com/feed/dsm-psychiatric-diagnosis-meaningless-study-says #dsm #psychiatry #dsm5 #trauma #ptsd #depression #anxiety #mentalhealth https://www.sciencedirect.com/science/article/abs/pii/S0165178119309114?via%3Dihub #fda #mdma #studydesign #heterogeneity #litreview
https://psychedelic-institute-of-mental-health.ghost.io/does-the-psychedelic-experience-matter/ still working on this one, but it’s coming together — #psychedelics #psychedelic #ketamine #fda #mdma #mdmaassistedpsychotherapy #mdmaassistedtherapy #ketamine #Ketamineassistedtherapy #ketamineassistedpsychotherapy #psychedelic #psychedelics #psychedelictherapy #psychedelicassistedpsychotherapy #nde #mysticalexperience #therapycult #phenomenology #consciousness #neuroscience #studydesign #psychedelicresearch #psychotherapy #lsd #dmt #psilocybin #psilocin #ayahausca
Psychedelic Institute of Mental Health · Psychedelic Therapy: Does the psychedelic experience matter?Part of an ongoing review of the literature on ketamine psychedelic-assisted psychotherapy
In the 2022 paper "Toward Synergies of Ketamine and Psychotherapy” (Mathai, et al, 2022) *pdf, researchers write:
"it is valuable to recognize the similarities between ketamine and classic (serotonergic) psychedelics such as psilocybin and lysergic acid diethylamide (LSD)
https://www.psychiatrist.com/jcp/ketamine-plus-psychotherapy-for-ptsd/ #ketamine #psychotherapy #ptsd #fda #mdma #studydesign #research #psychedelics #psychedelic #ketamineassistedpsychotherapy #psychedelicassistedtherapy #psychedelicassistedpsychotherapy #ketaminetherapy #metaanalysis #litreview #psychotherapy #mentalhealth
#Psilocybin Versus #ketamine in Treatment-Resistant #depression (PSIKET_001) #clinicaltrial #studydesign #psychedelics #psychedelic #psychedelicresearch #fda #mdma Now recruiting in #czechrepublic
ClinicalTrials.gov ID NCT05383313
Sponsor: National Institute of Mental Health, Czech Republic https://clinicaltrials.gov/study/NCT05383313?intr=Ketamine%20psilocybin&rank=5 — This study does direct comparison with an active placebo midazolam which is not an #antidepressant
https://clinicaltrials.gov/study/NCT05746572?term=mdma%20ptsd%20and%20emory&rank=1&a=8 Emory University plans #fda Phase 2 study of #mdma plus a type of behavioral #psychotherapy called Exposure Therapy for the treatment of #ptsd — This study is unrelated to the MAPS/Lykos new drug application for #mdmaassistedtherapy and a reminder #psychedelic #research is robust and ongoing. #studydesign should include blinding with #ketamine and comparison to #cognitivebehavioraltherapy #psychedelics
Top FDA official overrules staff to approve gene therapy that failed trial - https://apple.news/AXkboQ5CsQXCzdmNLXodiMg #fda #mdma #psychedelics #psychedelic #studydesign #research
https://finance.yahoo.com/news/atai-life-sciences-announces-beckley-110000192.html Phase 1/2a Trial of ELE-101 (IV #psilocin for Major Depressive Disorder, with Initial Results from Phase 1, First Patients Dosed in Phase 2a #depression #psychedelic #psychedelics #psychedelicresearch #fda #esketamine #ketamine #psilocybin #psychedelicresearch #studydesign #fda Will they blind with #ketamine by iv, study with / without #cognitivebehavioraltherapy & compare to existing #antidepressants ?
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"During these trials, the participants were randomly assigned to receive one of three commonly prescribed antidepressant medications (escitalopram, sertraline or venlafaxine extended release (XR) (n = 164)) or an established behavioral intervention that integrated problem-solving with behavioral activation, compared with treatment as usual (n = 86)” #psychedelic #studydesign #fda — That established behavioral intervention was #psychotherapy using ideas that became #cognitivebehavioraltherapy
https://www.nature.com/articles/s41562-023-01787-3 A systematic review and meta-analysis of transdiagnostic cognitive behavioural therapies for emotional disorders (Schaeuffele, et al, 2024) #cognitivebehavioraltherapy #metaanalysis #psychedelics #psychedelic #fda #mdma #ketamine #psychedelicassistedpsychotherapy #studydesign #depression #anxiety #psychotherapy
https://www.sciencedirect.com/science/article/abs/pii/S0165178123005358?via%3Dihub Cognitive behavioral therapy following esketamine for major #depression and suicidal ideation for relapse prevention: The CBT-ENDURE randomized clinical trial study protocol (Kitay, et al, 2023) proposes pilot #studydesign with #fda approved #ketamine formulation with #cognitivebehavioraltherapy #psychedelics #psychedelicresearch #mdma #mdmaassistedtherapy #ketaminetherapy #ketamineassistedpsychotherapy
https://pubmed.ncbi.nlm.nih.gov/38654374/ Severe enduring anorexia nervosa (SE-AN) treatment options and their effectiveness: a review of literature (Marcolini, et al, 2024) on #anorexia #ketamine #psychotherapy #cognitivebehavioraltherapy found to be valid alternative to hospitalization and more effective than “specialist supportive clinical management” #fda #studydesign #mdma #psychedelicassistedpsychotherapy #ketamineassistedpsychotherapy
https://pubmed.ncbi.nlm.nih.gov/38782821/ Psychedelic-assisted psychotherapy: where is the psychotherapy research? (Aday, 2024) #psychedelics #fda #mdma #ketamine #psilocybin #psychedelicassistedpsychotherapy #psychotherapy #psychedelic #studydesign #cognitivebehavioraltherapy — Where is the #research ? There are 60k entries for cbt on pubmed. https://pubmed.ncbi.nlm.nih.gov/?term=cognitive+behavioral+therapy&sort=date #research #psychedelictherapy