Create accountLogin

Recent searches

No recent searches

Search options

Only available when logged in.
toad.social is one of the many independent Mastodon servers you can use to participate in the fediverse.
Mastodon server operated by David Troy, a tech pioneer and investigative journalist addressing threats to democracy. Thoughtful participation and discussion welcome.

Administered by:

Server stats:

334
active users

toad.social: AboutProfiles directoryPrivacy policy

Mastodon: AboutGet the appKeyboard shortcutsView source codev4.3.7

#epigenetics

3 posts3 participants0 posts today
Public *
neville park

"Jo had no idea what a perfect correspondent heʼd found. Because the only audience my mom respects more than her entomological peers is small children…

"In September 2022, Jo presented his research to scientists at Shinshu University. Then at Tsukuba University and Saga University. He also graduated from second grade."

Reporter Annie Rosenthal's mother, Martha Weiss, helped discover that moths can remember things they learned when they were caterpillars. A young boy from Japan writes to her that he wants to replicate the experiment with swallowtail butterflies. With her help, he does. Then he sets his sights on an even more ambitious goal: testing whether butterflies can remember things *their parents* learned.

This was lovely and I teared up a bit just reading it. About generational memory, kindness, nurturing young scientists, Japanese bug culture, and more.

signalhill.fm/issue-one/#cater

Transcript (PDF): signalhill.fm/content/files/20

Cut-out of Martha Rosenthal, a middle-aged white woman, with Jo Nagai, a young Japanese boy, against a green background. Childlike drawings of butterfly wings, pink and black and yellow, are shown behind them.
#bugstodon#entomology#butterflies
Public
flo

Epigenetic signatures of intergenerational exposure to violence in three generations of Syrian #refugees

https://www.nature.com/articles/s41598-025-89818-z #trauma #syria #epigenetics

NatureEpigenetic signatures of intergenerational exposure to violence in three generations of Syrian refugees - Scientific ReportsMaternal trauma influences infant and adult health outcomes and may impact future generations through epigenetic modifications such as DNA methylation (DNAm). Research in humans on the intergenerational epigenetic transmission of trauma effects is limited. In this study, we assessed DNAm signatures of war-related violence by comparing germline, prenatal, and direct exposures to violence across three generations of Syrian refugees. We compared families in which a pregnant grandmother versus a pregnant mother was exposed to violence and included a control group with no exposure to war. We collected buccal swab samples and survey data from mothers and 1–2 children in each of 48 families (n = 131 participants). Based on an epigenome-wide association study (EWAS), we identified differentially methylated regions (DMPs): 14 were associated with germline and 21 with direct exposure to violence. Most DMPs showed the same directionality in DNAm change across germline, prenatal, and direct exposures, suggesting a common epigenetic response to violence. Additionally, we identified epigenetic age acceleration in association with prenatal exposure to violence in children, highlighting the critical period of in utero development. This is the first report of an intergenerational epigenetic signature of violence, which has important implications for understanding the inheritance of trauma.
Continued thread
Public
Karl Theodor

„Wir müssen über #Cannabis diskutieren und dafür möchte ich die #Million einsetzen. Die #Politik muss sich endlich dieser #Debatte stellen.

hanfverband.de/millionaerswahl

#EndFossilFuels #EndFossilGas
#Traumata #fridaysforfuture #lastgeneration #climatecrisis #klimakatastrophe
#Epigenetics
#Endocannabinoide #Cannabinoide
#Kipppunkte #biohazard #hanf #hemp #climate

“The beginning of knowledge is the discovery of something we do not understand.”
― Frank Herbert #Zeitdilatation

26.01.2014 | Pressemitteilung | Georg Wurth Millionärswahl: Hanfverband gewinnt Million für die Legalisierung! Pressemitteilung des Deutschen Hanf Verbandes (DHV) Mit dem Sieg von Georg Wurth bei der Millionärswahl von Pro7 und Sat.1 am vergangenen Samstag feiert der Deutsche Hanf Verband einen seiner bisher größten Erfolge. Mit dem Gewinn wird der DHV die Debatte um einen sinnvolleren Umgang mit Cannabis in Deutschland vorantreiben. Georg Wurth erklärt hierzu: „Wir müssen über Cannabis diskutieren und dafür möchte ich die Million einsetzen. Die Politik muss sich endlich dieser Debatte stellen. In Colorado wird inzwischen völlig legal Cannabis verkauft, der US-Bundesstaat Washington und Uruguay als erste Nation sind gerade dabei, die entsprechenden Beschlüsse umzusetzen. Dies zeigt, dass eine andere Cannabispolitik möglich ist! Es geht nicht um eine Verharmlosung von Cannabis, sondern um eine Alternative zum Verbot. Die Cannabisprohibition ist gescheitert, schädlich und teuer – wir möchten den bestehenden Schwarzmarkt durch einen regulierten Markt mit Jugend- und Verbraucherschutz ersetzen.
Public *
ma𝕏pool

3rd method if inheritance besides DNA and RNA: Amyloid-like protein structures that have the ability to replicate making them possible inheritance vectors.

Noncanonical inheritance of phenotypic information by protein amyloids nature.com/articles/s41556-024

>we identify amyloid-like protein structures that are stably inherited in wild-type animals and influence traits. Their perturbation by genetic, environmental or pharmacological treatments leads to developmental phenotypes that can be epigenetically passed onto progeny.

NatureNoncanonical inheritance of phenotypic information by protein amyloids - Nature Cell BiologyEroglu et al. describe protein amyloid structures that are stably inherited across generations and transmit epigenetic memory in Caenorhabditis elegans. MSTR protein loss results in a transgenerational feminization phenotype through ectopic GLD-1 expression.
#biology#cellbiology#epigenetics
Public
Moritz Bartl

"There is a growing understanding that mental illness has a crucial physical component and may cause disturbances of mind and body which strongly emphasizes a crucial role of psychotherapy focused on early stressful experiences mainly during critical developmental periods including prenatal and perinatal traumas."

"#epigenetics […] will likely be one of the most important areas of scientific research."

Janov, A. Epigenetics and Primal Therapy. Act Nerv Super 57, (2015). doi.org/10.1007/BF03379941

SpringerLinkEpigenetics and Primal Therapy - Activitas Nervosa SuperiorEpigenetics is focused on the study of how experience changes an individual’s genetic expression, previously considered inalterable. Recent pioneering research indicates that epigenetics is revolutionizing the study of mental health and challenging the belief that DNA is destiny. Moreover, in terms of the history of science, the new developments augur the convergence of previously distinct fields, psychology and biology. There is a growing understanding that mental illness has a crucial physical component and may cause disturbances of mind and body which strongly emphasis a crucial role of psychotherapy focused on early stressful experiences mainly during critical developmental periods including prenatal and perinatal traumas.
ExploreLive feeds
About